Boc-N-amido-PEG3-sulfonic acid
- CAS No.
- 1817735-32-2
- Chemical Name:
- Boc-N-amido-PEG3-sulfonic acid
- Synonyms
- Boc-NH-PEG3-SO3H;Boc-NH-PEG3-sulfonic acid;Boc-N-amido-PEG3-sulfonic acid;5,8,11-Trioxa-2-azatridecanoic acid, 13-sulfo-, 1-(1,1-dimethylethyl) ester
- CBNumber:
- CB93162913
- Molecular Formula:
- C13H27NO8S
- Molecular Weight:
- 357.42
- MDL Number:
- MFCD29042344
- MOL File:
- 1817735-32-2.mol
Boc-N-amido-PEG3-sulfonic acid Chemical Properties,Uses,Production
Description
t-Boc-N-amido-PEG3-sulfonic acid is a PEG linker containing a t-Boc protected amine group and a sulfonic acid. The t-Boc protecting group can be removed under acidic conditions so that the amine can be further reacted. The sulfonic acid can undergo esterification, halogenation and displacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Boc-NH-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Boc-N-amido-PEG3-sulfonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32219 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | viola@huatengsci.com | China | 5874 | 58 |
Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1986 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
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