ChemicalBook >> CAS DataBase List >>3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE

CAS No.
112192-04-8
Chemical Name:
3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
Synonyms
Roxindole;RoxindoleHCl;Roxindole [inn];ROXINDOLE HYDROCHLORIDE;1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-;3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol;3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol;3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
CBNumber:
CB9330973
Molecular Formula:
C23H26N2O
Molecular Weight:
346.47
MDL Number:
MFCD04038810
MOL File:
112192-04-8.mol
Last updated:2023-05-04 17:34:31

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Properties

Melting point >165°C (dec.)
Boiling point 575.7±50.0 °C(Predicted)
Density 1.173±0.06 g/cm3(Predicted)
storage temp. Desiccate at -20°C
solubility DMSO (Slightly), Water (Slightly)
pka 10.15±0.40(Predicted)
form Solid
color Pale Beige to Light Beige
Stability Hygroscopic
FDA UNII 43227SMS0O

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1559 Roxindolehydrochloride ≥98%(HPLC) 112192-04-8 10 $181 2021-12-16 Buy
Tocris 1559 Roxindolehydrochloride ≥98%(HPLC) 112192-04-8 50 $738 2021-12-16 Buy
Usbiological 256504 Roxindole hydrochloride 112192-04-8 10mg $423 2021-12-16 Buy
American Custom Chemicals Corporation API0012443 ROXINDOLE 95.00% 112192-04-8 5MG $503.71 2021-12-16 Buy
Product number Packaging Price Buy
1559 10 $181 Buy
1559 50 $738 Buy
256504 10mg $423 Buy
API0012443 5MG $503.71 Buy

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Roxindole Hydrochloride is a selective and potent presynaptic D-2 dopamine autoreceptor agonist.

Definition

ChEBI: Roxindole is a member of indoles. It has a role as an alpha-adrenergic antagonist and a serotonergic drug.

Biological Activity

Dopamine D 2 autoreceptor agonist, with affinity for D 3 , D 4 and 5-HT 1 receptors (pK i values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D 2 , D 3 , D 4 , 5-HT 1A , 5-HT 1B and 5-HT 1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo .

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE ROXINDOLE HYDROCHLORIDE Roxindole RoxindoleHCl 3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol 3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol Roxindole [inn] 1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]- 112192-04-8 Dopamine receptor