Pseudocoptisine chloride
- CAS No.
- 30044-78-1
- Chemical Name:
- Pseudocoptisine chloride
- Synonyms
- Isocoptisine chloride;Pseudocoptisine chloride;Isocoptisine,anti-amnestic,Pseudocoptisine chloride,cytokines,anti-inflammatory,Pseudocoptisine,pro-inflammatory,RAW 264.7,Cholinesterase (ChE),inhibit,Inhibitor
- CBNumber:
- CB93340603
- Molecular Formula:
- C19H14ClNO4
- Molecular Weight:
- 355.77
- MDL Number:
- MFCD33548929
- MOL File:
- 30044-78-1.mol
Pseudocoptisine chloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0158969 | Pseudocoptisinechloride 99.17% | 30044-78-1 | 5mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-0158969 | Pseudocoptisinechloride 99.17% | 30044-78-1 | 10mg | $480 | 2021-12-16 | Buy |
| ChemScene | CS-0158969 | Pseudocoptisinechloride 99.17% | 30044-78-1 | 25mg | $950 | 2021-12-16 | Buy |
| ChemScene | CS-0158969 | Pseudocoptisinechloride 99.17% | 30044-78-1 | 50mg | $1450 | 2021-12-16 | Buy |
| ChemScene | CS-0158969 | Pseudocoptisinechloride 99.17% | 30044-78-1 | 100mg | $2250 | 2021-12-16 | Buy |
Pseudocoptisine chloride Chemical Properties,Uses,Production
Biological Activity
Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM. Anti-inflammatory and anti-amnestic effects.
in vitro
Pseudocoptisine (0, 60, 90 μM; 1 hour) dose-dependently inhibited LPS-induced NO production in RAW264.7 cells.
Pseudocoptisine (30-90 μM; 1 hour; RAW264.7 cells) significantly reduces the LPS-induced TNF-α and IL-6 production and their mRNA expressions.
Pseudocoptisine acetate reduces levels of the pro-inflammatory mediators, such as, iNOS, COX-2, TNF-alpha, and IL-6 through the inhibition of NF-kappaB activation via the suppression of ERK and p38 phosphorylation in RAW 264.7 cells.
in vivo
The anti-amnesic activities of Pseudocoptisine in mice on the learning and memory impairments induced by scopolamine (1.0 mg/kg, ip) are examined. Pseudocoptisine (2.0 mg/kg, po) significantly reverses cognitive impairments in mice by passive avoidance test.
Pseudocoptisine chloride Preparation Products And Raw materials
Raw materials
Preparation Products
Pseudocoptisine chloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Shijiazhuang Tancheng Biological Technology Co., Ltd | 0311-84309789 13833149888 | tanchengchem@163.com | China | 32 | 58 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
| Hubei Wande Chemical Co., Ltd | 027-59210159 15377098680 | 1148280011@qq.com | China | 9994 | 58 |
| Tianmen Hengchang Chemical Co., Ltd | 027-59322316 15172518801 | 1208480077@qq.com | China | 9944 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | 18051384581 | sales@chemhifuture.com | China | 2996 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |