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2',3',5'-Tri-O-acetylinosine

2',3',5'-Tri-O-acetylinosine structure

CAS No.: 3181-38-2

Chemical Name:: 2',3',5'-Tri-O-acetylinosine

Synonyms: Ai3-52250;NSC 66386;Einecs 221-669-7;2',3',6'-TAc-Ino;-TRIACETYLINOSINE;Inosine triacetate;2,3,5-TRIACETYLINOS;Direct red brown MN;2',3',5'-Triacetylin;Adenosine Impurity 38

CBNumber:: CB9354351

Molecular Formula:: C16H18N4O8

Molecular Weight:: 394.34

MDL Number:: MFCD00038617

MOL File:: 3181-38-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:49

Product description	Number	Pack Size	Price
ACETIC ACID 3,4-DIACETOXY-5-(6-HO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER Aldrich^CPR	R701467	1 unit	$185
ACETIC ACID 3,4-DIACETOXY-5-(6-HO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER Aldrich	R701467	25mg	$179
2',3',5'-Tri-O-acetylinosine	NT06708	50g	$225
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate 97%	P000717979	100g	$286
2',3',5'-Tri-O-acetylinosine	NT06708	100g	$420
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2',3',5'-Tri-O-acetylinosine Properties

Melting point	234-236°C
Boiling point	620.7±65.0 °C(Predicted)
Density	1.62±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Methanol (Sparingly), Water (Sparingly)
form	Solid
pka	2.96±0.20(Predicted)
color	White
Stability	Freezer
InChIKey	SFEQTFDQPJQUJM-XNIJJKJLSA-N
SMILES	C(OC(=O)C)[C@H]1O[C@@H](N2C3C(=C(N=CN=3)O)N=C2)[C@H](OC(=O)C)[C@@H]1OC(=O)C
CAS DataBase Reference	3181-38-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Safety Statements	24/25
WGK Germany	3
HS Code	29349990

2',3',5'-Tri-O-acetylinosine price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	R701467	ACETIC ACID 3,4-DIACETOXY-5-(6-HO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER Aldrich^CPR	3181-38-2	1 unit	$185	2025-07-31	Buy
Sigma-Aldrich	R701467	ACETIC ACID 3,4-DIACETOXY-5-(6-HO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER Aldrich	3181-38-2	25mg	$179	2024-03-01	Buy
Biosynth Carbosynth	NT06708	2',3',5'-Tri-O-acetylinosine	3181-38-2	50g	$225	2021-12-16	Buy
Ark Pharm	P000717979	(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate 97%	3181-38-2	100g	$286	2021-12-16	Buy
Biosynth Carbosynth	NT06708	2',3',5'-Tri-O-acetylinosine	3181-38-2	100g	$420	2021-12-16	Buy

Product number	Packaging	Price	Buy
R701467	1 unit	$185	Buy
R701467	25mg	$179	Buy
NT06708	50g	$225	Buy
P000717979	100g	$286	Buy
NT06708	100g	$420	Buy

2',3',5'-Tri-O-acetylinosine Chemical Properties,Uses,Production

Description

2',3',5'-Tri-O-acetylinosine has been shown to inhibit the growth of cancer cells, and is also an efficient method for bond cleavage and radiation protection. 2',3',5'-Tri-O-acetylinosine has been shown to bind to pyridinium ions, and it has been used in the synthesis of tetrapeptides with hydroxyl groups or alkylation.

Chemical Properties

White Crystalline Solid

Uses

2',3',5'-Tri-O-acetylinosine is an intermediate used for the synthesis of 6-substituted purine ribosides

Uses

An intermediate used for the synthesis of 6-substituted purine ribosides.

Synthesis

108-24-7

58-63-9

3181-38-2

To a suspension of inosine (10 g, 37.3 mmol) and a catalytic amount of 4-dimethylaminopyridine (DMAP) in acetonitrile (60 mL) were sequentially added triethylamine (20 mL, 143 mmol) and acetic anhydride (12.5 mL). The reaction mixture was stirred at room temperature for 1 hour, followed by the slow addition of methanol (5 mL). After continued stirring for 5 min, the reaction solution was concentrated under reduced pressure to give a white solid. The solid was washed with isopropanol to afford (2R,3R,4R,5R)-2-(acetyloxymethyl)-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate (triacetoxyinosine, 12.1 g, 82% yield).

References

[1] Organic and Biomolecular Chemistry, 2005, vol. 3, # 3, p. 462 - 470
[2] Synthesis, 2003, # 17, p. 2639 - 2642
[3] Journal of the American Chemical Society, 1997, vol. 119, # 32, p. 7423 - 7433
[4] Journal of Organic Chemistry, 1985, vol. 50, # 15, p. 2664 - 2667
[5] Chemistry - A European Journal, 2015, vol. 21, # 33, p. 11634 - 11643

2',3',5'-Tri-O-acetylinosine Preparation Products And Raw materials

Raw materials

Acetic anhydride 1-Acetylimidazole Inosine Acetonitrile 4-Dimethylaminopyridine

Triethylamine

1of2

Preparation Products

2-(6-ethylaminopurin-9-yl)-5-(hydroxymethyl)oxol 6-Chloropurine ribonucleoside

2',3',5'-Tri-O-acetylinosine Suppliers

Global( 202)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Measure Life Technology Co., LTD	+8613343730176	2924244016@qq.com	China	83	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	3999	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16514	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13505	58
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58

Supplier	Advantage
Hangzhou Measure Life Technology Co., LTD	58
Chongqing Chemdad Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from 2',3',5'-Tri-O-acetylinosine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-13	2',3',5'-Tri-O-acetylinosine 3181-38-2	US $8.80-2.20 / kg	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2024-07-08	2',3',5'-TRI-O-ACETYLINOSINE 3181-38-2	US $1.00 / Kg	1Kg	98%	20T	Shaanxi Dideu Medichem Co. Ltd
2019-07-06	2',3',5'-TRIACETYLINOSINE 3181-38-2	US $2.00 / KG	1KG	98%	1ton	Career Henan Chemical Co

2',3',5'-Tri-O-acetylinosine
3181-38-2
US $8.80-2.20 / kg
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2',3',5'-TRI-O-ACETYLINOSINE
3181-38-2
US $1.00 / Kg
98%
Shaanxi Dideu Medichem Co. Ltd

2',3',5'-TRIACETYLINOSINE
3181-38-2
US $2.00 / KG
98%
Career Henan Chemical Co

3181-38-2(2',3',5'-Tri-O-acetylinosine)Related Search:

Inosine 2',3',5'-Triacetylinosine 2',3',5-TRI-O-ACETYL-8-BROMOGUANOSINE 2',3',5'-Triacetylguanosine 2',3',5'-TRI-O-ACETYLINOSINE

Tri-O-acetyl-8-(allyloxy)guanosine guanosine 2',3',5'-tribenzoate 2',3',5'-TRI-O-ACETYL-2N,2N-DIMETHYL-GUANOSINE

1of2

INOSINE 2',3',5'-TRIACETATE ACETICACID3,4-DIACETOXY-5-(6-HO-PURIN-9-YL)-TETR 2,3,5-TRIACETYLINOS 2',3',5'-Tri-O-acetyl-D-inosine 2,3,5-TRIACETYLINOSINE CRYSTALLINE (2R,3S,4R,5R)-2-(ACETOXYMETHYL)-5-(6-OXO-1H-PURIN-9(6H)-YL)TETRAHYDROFURAN-3,4-DIYL DIACETATE 2'',3'',5''-TRI-O-ACETYL-INOSIN 2'-O,3'-O,5'-O-Triacetyl-6-hydroxy-6-deaminoadenosine 2'-O,3'-O,5'-O-Triacetylinosine 9-(2-O,3-O,5-O-Triacetyl-β-D-ribofuranosyl)-1H-purine-6(9H)-one 9-(2-O,3-O,5-O-Triacetyl-β-D-ribofuranosyl)-9H-purine-6-ol Inosine triacetate 2',3',5'-Triacetylinosine Ai3-52250 Einecs 221-669-7 2',3',5'-Triacetylin NSC 66386 (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate ACETIC ACID 3,4-DIACETOXY-5-(6-HO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER ACETIC ACID (2R,3R,4R,5R)-4-ACETOXY-5-ACETOXYMETHYL-2-(6-OXO-1,6-DIHYDRO-PURIN-9-YL)-TETRAHYDRO-FURAN-3-YL ESTER 2',3',5'-TRI-O-ACETYLINOSINE -TRIACETYLINOSINE Direct red brown MN Ribavirin Impurity 14 (Triacetylinosine) 2',3',6'-TAc-Ino 2',3',5'-TRI-O-ACETYLINOSINE USP/EP/BP Adenosine Impurity 38 2',3',5'-Tri-O-inosine 2′,,3′,,5′,-TAc-Ino 3181-38-2 C16H18N4O8 Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides BioChemical Biochemicals and Reagents Bases & Related Reagents Nucleotides Pharmaceutical Raw Materials