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PRUNASIN

PRUNASIN structure

CAS No.: 99-18-3

Chemical Name:: PRUNASIN

Synonyms: Prunacin;PRUNASIN;d-prunasin;(r)-prunasin;Noguro Sakura;Wild cherry glycoside;(r)-benzeneacetonitril;Prunasin (6CI, 7CI, 8CI);D-MANDELONITRILE B-D-GLUCOSIDE;D-Mandelonitrile β-D-glucoside

CBNumber:: CB9677133

Molecular Formula:: C14H17NO6

Molecular Weight:: 295.29

MDL Number:: MFCD00049232

MOL File:: 99-18-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:59:15

Product description	Number	Pack Size	Price
D-Mandelonitrile β-D-glucoside ≥90% (LC/MS-ELSD)	SMB00173	1mg	$527
(R)-Prunasin ≥95%	15959	500μg	$103
(R)-Prunasin ≥95%	15959	1mg	$183
(R)-Prunasin ≥95%	15959	5mg	$602
(R)-Prunasin ≥95%	15959	500μg	$93
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PRUNASIN Properties

Melting point	138-148°C
Boiling point	527.0±50.0 °C(Predicted)
Density	1.45±0.1 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	12.71±0.70(Predicted)
color	White to off-white
Stability	Hygroscopic
Major Application	metabolomics vitamins, nutraceuticals, and natural products
Cosmetics Ingredients Functions	SKIN CONDITIONING
InChI	InChI=1/C14H17NO6/c15-6-9(8-4-2-1-3-5-8)20-14-13(19)12(18)11(17)10(7-16)21-14/h1-5,9-14,16-19H,7H2/t9-,10+,11+,12-,13+,14+/s3
InChIKey	ZKSZEJFBGODIJW-OAWZEMCWNA-N
SMILES	O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@H](C1C=CC=CC=1)C#N \|&1:1,2,3,5,7,12,r\|
EWG's Food Scores	1
FDA UNII	14W4BPM5FB
UNSPSC Code	12352205
NACRES	NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08

Signal word

Danger

Hazard statements

H301-H360

Precautionary statements

P201-P301+P310+P330

Hazard Codes

Risk Statements

36/37/38-25-60

Safety Statements

26-36/37/39-61-45

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

RTECS

UL3420000

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Oral
Repr. 1B

NFPA 704

	0
2		0

PRUNASIN price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SMB00173	D-Mandelonitrile β-D-glucoside ≥90% (LC/MS-ELSD)	99-18-3	1mg	$527	2026-04-30	Buy
Cayman Chemical	15959	(R)-Prunasin ≥95%	99-18-3	500μg	$103	2026-04-30	Buy
Cayman Chemical	15959	(R)-Prunasin ≥95%	99-18-3	1mg	$183	2026-04-30	Buy
Cayman Chemical	15959	(R)-Prunasin ≥95%	99-18-3	5mg	$602	2026-04-30	Buy
Cayman Chemical	15959	(R)-Prunasin ≥95%	99-18-3	500μg	$93	2024-03-01	Buy

Product number	Packaging	Price	Buy
SMB00173	1mg	$527	Buy
15959	500μg	$103	Buy
15959	1mg	$183	Buy
15959	5mg	$602	Buy
15959	500μg	$93	Buy

PRUNASIN Chemical Properties,Uses,Production

Description

(R)-Prunasin is a cyanogenic glucoside that is the precursor to amygdalin, a bitter component found in species of the genera Prunus and Olinia. It can be degraded to hydrogen cyanide, glucose, and benzaldehyde by the action of prunasin hydrolase and mandelonitrile lyase and possesses inhibitory effects on plant growth. (R)-Prunasin reportedly inhibits rat DNA polymerase β, which performs base excision repair required for DNA maintenance and replication, with an IC₅₀ value of 98 μM.

Chemical Properties

White Solid

Uses

Used in the synthesis of cyanogen glycoside. A component of antiperspirants, deodorants, body soaps, shampoos, hair rinses, and hair

Definition

ChEBI: (R)-prunasin is a prunasin.

Enzyme inhibitor

This cyanogenic glucoside (FW = 295.29 g/mol; CAS 99-18-3), also known as D(R)-mandelonitrile-b-D-glucoside, is readily obtained from amygdalin and is found in the pits of Prunus serotina. Prunasin is soluble in water and will give rise to prulaurasin (i.e., the diastereoisomeric mixture of DL(RS)- mandelonitrile-b-D-glucoside [i.e., prunasin and sambunigrin]). Target(s): DNA-directed DNA polymerase; DNA polymerase b; and a,a trehalase.

References

[1] RAQUEL SáNCHEZ-PéREZ. Prunasin hydrolases during fruit development in sweet and bitter almonds.[J]. Plant Physiology, 2012, 158 4: 1916-1932. DOI: 10.1104/pp.111.192021
[2] Y MIZUSHINA. The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta.[J]. Journal of biochemistry, 1999, 126 2: 430-436. DOI: 10.1093/oxfordjournals.jbchem.a022468

PRUNASIN synthesis

Synthesis of PRUNASIN from Benzaldehyde

PRUNASIN Preparation Products And Raw materials

Raw materials

2,3,4,6-TETRA-O-ACETYL-ALPHA-D-GLUCOPYRANOSYL TRICHLOROACETIMIDATE (R)-Prunasin Tetraacetate (αR)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide Benzaldehyde

Preparation Products

D-arabino-hexosulose bis(phenylhydrazone) (R)-(+)-ALPHA-HYDROXYBENZENE-ACETONITRILE Malonic acid

PRUNASIN Suppliers

Global( 125)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+8617392709771	1097@dideu.com	China	3996	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3751	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3461	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9540	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
BOC Sciences	58
career henan chemical co	58
Hubei Ipure Biology Co., Ltd	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	58
Finetech Industry Limited	58
TargetMol Chemicals Inc.	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from PRUNASIN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-24	PRUNASIN 99-18-3	US $0.00-0.00 / KG	1KG	99.0%	1000KG	Shaanxi Dideu Medichem Co. Ltd
2025-12-24	Methyl gallate 99-18-3	US $0.00-0.00 / KG	1KG	99.0%	1000KG	Shaanxi Dideu Medichem Co. Ltd
2024-11-28	Prunasin 99-18-3	US $3500.00 / g	1g	98	50 Kg	R&D Scientific Inc.

PRUNASIN
99-18-3
US $0.00-0.00 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

Methyl gallate
99-18-3
US $0.00-0.00 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

Prunasin
99-18-3
US $3500.00 / g
98
R&D Scientific Inc.

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Mandelonitrile PRUNASIN Amygdalin PRUNASIN(RG) AMYGDALIN TRIHYDRATE

PHENYL-[3,4,5-TRIHYDROXY-6-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXYMETHYL)-TETRAHYDRO-PYRAN-2-YLOXY]-ACETONITRILE HOLOCALIN prunasin hydrolase

1of4

D-Mandelonitrile β-D-glucoside (R)-α-(β-D-Glucopyranosyloxy)benzeneacetonitrile (αR)-α-(β-D-Glucopyranosyloxy)-α-phenylacetonitrile [(αR)-α-Cyanobenzyl]β-D-glucopyranoside Prunacin (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyacetonitrile (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-ethanenitrile (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-acetonitrile PENTAMETHYL-6-HYDROXYCHROMAN, 2,2,5,7,8-(RG) Benzeneacetonitrile, a-(b-D-glucopyranosyloxy)-, (aR)- D-MANDELONITRILE-BETA-D-GLUCOSIDE PRUNASIN (R)-(beta-D-glucopyranosyloxy)phenylacetonitrile D-MANDELONITRILE B-D-GLUCOSIDE (r)-alpha-(beta-d-glucopyranosyloxy)benzene-acetonitrile (r)-benzeneacetonitril (r)-prunasin d-prunasin Noguro Sakura Benzeneacetonitrile, α-(β-D-glucopyranosyloxy)-, (αR)- Wild cherry glycoside Prunasin (6CI, 7CI, 8CI) D-Mandelonitrile β-D-glucoside (R)-2-Phenyl-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)acetonitrile 99-18-3 Chiral Reagents Miscellaneous Natural Products Aromatics Carbohydrates & Derivatives