ChemicalBook >> CAS DataBase List >>4-Methylpyridin-2-amine


Chemical Name:
2-AMINO-4-METHYLPYRIDINE;2-AMINO-4-PICOLINE;Aminopicoline;w45;W 45;4M2AP;ra1226;RA 1226;NSC 1490;NSC 6972
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:
Last updated:2023-06-30 17:01:55

4-Methylpyridin-2-amine Properties

Melting point 96-99 °C (lit.)
Boiling point 230 °C (lit.)
Density 1.0275 (estimate)
vapor pressure 3.71Pa at 25℃
refractive index 1.5560 (estimate)
Flash point 118 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: freely soluble
form Flakes
pka pK1: 7.48(+1) (25°C)
color Slightly yellow to beige or brown
Water Solubility SOLUBLE
Sensitive Hygroscopic
Merck 14,466
BRN 107066
LogP 0.56-1.08
CAS DataBase Reference 695-34-1(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 2-Pyridinamine, 4-methyl-(695-34-1)
EPA Substance Registry System 2-Pyridinamine, 4-methyl- (695-34-1)


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
Signal word  Danger
Hazard statements  H301+H311+H331-H373
Precautionary statements  P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P314
Hazard Codes  T
Risk Statements  45-46-60-61-8-21-25-26-34-42/43-48/23-50/53-36/37/38-33-23/24/25
Safety Statements  53-45-60-61-37/39-28A-26-36/37/39
RIDADR  UN 3086 6.1/PG 1
WGK Germany  3
RTECS  TJ5150000
HazardClass  6.1
PackingGroup  II
HS Code  29333999
Toxicity LD50 oral in rat: 200mg/kg
NFPA 704
3 1

4-Methylpyridin-2-amine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 123080 2-Amino-4-methylpyridine 99% 695-34-1 100g $57.6 2023-06-20 Buy
TCI Chemical A0402 2-Amino-4-methylpyridine >98.0%(GC)(T) 695-34-1 25g $65 2023-06-20 Buy
TCI Chemical A0402 2-Amino-4-methylpyridine >98.0%(GC)(T) 695-34-1 500g $390 2023-06-20 Buy
Alfa Aesar A14177 2-Amino-4-methylpyridine, 98% 695-34-1 25g $24.7 2023-06-20 Buy
Alfa Aesar A14177 2-Amino-4-methylpyridine, 98% 695-34-1 100g $36.2 2023-06-20 Buy
Product number Packaging Price Buy
123080 100g $57.6 Buy
A0402 25g $65 Buy
A0402 500g $390 Buy
A14177 25g $24.7 Buy
A14177 100g $36.2 Buy

4-Methylpyridin-2-amine Chemical Properties,Uses,Production

Chemical Properties

Light yellow to brown flakes


2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methyl-pyridinium 2-hy-droxy-benzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.


Intermediate, medicine.

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 4554, 2007 DOI: 10.1021/jo070189y

General Description

2-Amino-4-methylpyridine acts as ligand and forms methoxo-bridged copper(II) complexes.

Biochem/physiol Actions

2-Amino-4-methylpyridine inhibits the activity of inducible NO synthase isolated from mouse RAW 264.7 cells in vitro.

Purification Methods

Crystallise it from EtOH or a 2:1 *benzene/acetone mixture, and dry it under vacuum as in the prevous entry. [Beilstein 22/9 V 325.]

Global( 624)Suppliers
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View Lastest Price from 4-Methylpyridin-2-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-4-Methyl-Pyridin pictures 2023-07-01 2-Amino-4-Methyl-Pyridin
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
4-Methylpyridin-2-amine pictures 2023-03-03 4-Methylpyridin-2-amine
US $60.00 / kg 1kg 99% 100 tons Hebei Duling International Trade Co. LTD
2-Amino-4-methylpyridine pictures 2023-01-31 2-Amino-4-methylpyridine
US $100.00 / KG 1KG 99% 5000kg/week Hebei Mojin Biotechnology Co., Ltd
99.995% trace Metals basis w45raschig 4-METHYL-2-PYRIDYLAMINE 4-METHYLPYRIDIN-2-AMINE 4-METHYL-PYRIDIN-2-YLAMINE AKOS BBS-00004343 AKOS 91145 TIMTEC-BB SBB004354 OTAVA-BB BB7015122364 SODIUM DICHROMATE 2H2O SODIUM DICHROMATE-2-HYDRATE SODIUM DICHROMATE, HYDROUS SODIUM BICHROMATE DIHYDRATE AURORA 11319 2-Amino-4-Methylpyridine,Nevirapine 2-Pyridinamine,4-methyl-(9CI) 2-AMINO-4-METHYL PYRODINE 2-AMINO-4-METHYL PYRIDINE 4-METHYLPYRIDIN-2-YLAMINE 2-Amino-4-methylpyridine, 98+% NSC 1490 NSC 176165 NSC 6972 2-AMINO-4-METHYLPYRIDINE FOR SYNTHESIS 2-Amino-4-methylpyridine ,99% 2-Amino-4-picoline,98% 2-AMino-4-picoline, 98% 100GR 2-Amino-4-picoline, 4-Methylpyridin-2-amine 4M2AP 4-Methyl-2-aminopyridine 4-Methyl-2-pyridamine 4-methyl-2-pyridinamin 4-Methyl-2-pyridinamine 4-Picoline, 2-amino- alpha-Amino-gamma-picoline Ascensil component of Ascensil component of Askensil Methyl-4 amino-2-pyridine methyl-4amino-2-pyridine Pyridine, 2-amino-4-methyl- RA 1226 ra1226 VMI 20-4 W 45 W 45 Raschig Rifaximin EP Impurity A 2-amino-4-methyl-pyridin 2-amino-4-picolin 2-Amino-gamma-picoline 2-Aminop-4-picoline 2-Pyridinamine,4-methyl- w45 Rifaximin impurities Rifaximin Impurity 1 (Rifaximin EP Impurity A) 2-Amino-4-methylpyridine > 4-methylpyridine-2-amine 4-Methylpyridin-2-amine ISO 9001:2015 REACH 695-34-1 4-Methylpyridin-2-amine