ChemicalBook >> CAS DataBase List >>proquazone
proquazone
- CAS No.
- 22760-18-5
- Chemical Name:
- proquazone
- Synonyms
- 43-715;Arthrex;Biarsan;Biarison;SaH-43-715;proquazone;Proquazona;Proquazonum;Sandoz-43-715;7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
- CBNumber:
- CB9880256
- Molecular Formula:
- C18H18N2O
- Molecular Weight:
- 278.35
- MDL Number:
- MFCD00866169
- MOL File:
- 22760-18-5.mol
- MSDS File:
- SDS
Last updated:2023-09-04 16:42:00
| Melting point | 137-138° |
|---|---|
| Boiling point | 436.12°C (rough estimate) |
| Density | 1.1707 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| pka | 0.74±0.20(Predicted) |
| FDA UNII | 42VPJ2980S |
| ATC code | M01AX13 |
proquazone Chemical Properties,Uses,Production
Uses
Anti-inflammatory.
Uses
Proquazone is a non-steroidal anti-inflammatory drug.
Definition
ChEBI: Proquazone is a member of pyrimidines.
brand name
Arthrex (Novartis), Biarison (Swiss-Pharma, Egypt; Biochemie, Austria; ICN Alkaloida, Hungary; Sandoz, Finland, Turkey).
Clinical Use
Proquazone has been used successfully to treat rheumatoid polyarthritis. At 900 mg/d it is comparable in effect to 150 mg/d of indomethacin. Gastrointestinal disturbances are the principal adverse effects observed with its use.
Synthesis
Synthesis: proquazone is prepared by the
alkylation of 2-amino-4-methylbenzophenone
with 2-iodopropane in the presence of
sodium carbonate to give 4-methyl-2-[(1-
methylethyl)amino]benzophenone, which is
condensed with urethane in the presence of
zinc chloride at 190 ?C.
proquazone Preparation Products And Raw materials
Raw materials
Preparation Products
proquazone Suppliers
Global( 12)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Aikon International Limited | 025-66113011 13155353615 | qzhang@aikonchem.com | China | 15396 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49323 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 10008 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-400-8210725 | malulu@leyan.com | China | 40041 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4030 | 58 |
22760-18-5(proquazone )Related Search:
43-715
Biarison
Biarsan
SaH-43-715
Sandoz-43-715
7-Methyl-1-(1-methylethyl)-4-phenyl-2(1H)-quinazolinone
proquazone
2(1H)-Quinazolinone, 7-methyl-1-(1-methylethyl)-4-phenyl-
7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
Arthrex
Proquazona
Proquazonum
22760-18-5