amisometradine
- CAS No.
- 550-28-7
- Chemical Name:
- amisometradine
- Synonyms
- Rolicton;amisometradine;Aminoisometradin;Aminoisometradine;6-Amino-3-methyl-1-(2-methylallyl)uracil;6-amino-3-methyl-1-(2-methylallyl)pyrimidine-2,4-quinone;6-amino-3-methyl-1-(2-methylprop-2-enyl)pyrimidine-2,4-dione;6-azanyl-3-methyl-1-(2-methylprop-2-enyl)pyrimidine-2,4-dione;6-Amino-3-methyl-1-(2-methyl-2-propenyl)pyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 6-amino-3-methyl-1-(2-methyl-2-propen-1-yl)-
- CBNumber:
- CB9920813
- Molecular Formula:
- C9H13N3O2
- Molecular Weight:
- 195.22
- MDL Number:
- MFCD00867343
- MOL File:
- 550-28-7.mol
| Product description | Number | Pack Size | Price |
| Amisometradine | A633600 | 50mg | $340 |
| Amisometradine | A633600 | 100mg | $640 |
| 6-AMINO-3-METHYL-1-(2-METHYLPROP-2-EN-1-YL)-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 95.00% | API0010583 | 5MG | $503.27 |
| Melting point | 175° |
|---|---|
| Boiling point | 331.89°C (rough estimate) |
| Density | 1.1985 (rough estimate) |
| refractive index | 1.5100 (estimate) |
| storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.97±0.70(Predicted) |
| color | White to Pale Beige |
| Stability | Light Sensitive |
| FDA UNII | 30973N61ZF |
amisometradine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A633600 | Amisometradine | 550-28-7 | 50mg | $340 | 2021-12-16 | Buy |
| TRC | A633600 | Amisometradine | 550-28-7 | 100mg | $640 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010583 | 6-AMINO-3-METHYL-1-(2-METHYLPROP-2-EN-1-YL)-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 95.00% | 550-28-7 | 5MG | $503.27 | 2021-12-16 | Buy |
amisometradine Chemical Properties,Uses,Production
Originator
Rolicton,Searle,US,1956
Uses
Amisometradine is an oral diuretic.
Definition
ChEBI: Amisometradine is a pyrimidone.
Manufacturing Process
Preparation of the ethyl analog is as follows (methyl isocyanate is used in
amisometradine manufacture).
To a cooled and stirred solution of 142 parts of methallylamine in 900 parts of
benzene, 156 parts of ethyl isocyanate are added dropwise. Upon
concentration in vacuum N-ethyl-N'-methallylurea is obtained.
260 parts of this urea derivative are dissolved in 500 parts of acetic anhydride
and treated with 157 parts of cyanoacetic acid at 60°C and heated at that
temperature for 2 hours. The solution is then concentrated in vacuum to a
syrup. 100 parts of water are added and the vacuum distillation is repeated.
The remaining syrup contains a mixture of N-cyanoacetyl-N-ethyl-N'-
methallylurea and a small quantity of N-cyanoacetyl-N-methallyl-N'-ethylurea.
This syrup is treated with sufficient 20% sodium hydroxide solution to raise
the pH to 10. A violent reaction occurs. The reaction mixture is diluted with 50
parts of water, stirred, cooled and filtered. The material collected on the filter
is recrystallized from 10% ethanol to yield a mixture of 1-methallyl-3-ethyl-6-
amino-1,2,3,4-tetrahydro-2,4-pyrimidinedione and 1-ethyl-3-methallyl-6-
amino-1,2,3,4-tetrahydro-2,4-pyrimidinedione melting at about 157-159°C.
Therapeutic Function
Diuretic
amisometradine Preparation Products And Raw materials
Raw materials
Preparation Products
amisometradine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9080 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19961 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-81120477 17792793610 | 1033@dideu.com | China | 9963 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | cindy.yang@lgcgroup.com | China | 18003 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
View Lastest Price from amisometradine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-21 | Amisometradine
550-28-7
|
US $1520.00-2500.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Amisometradine
550-28-7
- US $1520.00-2500.00 / mg
- TargetMol Chemicals Inc.
