chlormerodrin
- CAS No.
- 62-37-3
- Chemical Name:
- chlormerodrin
- Synonyms
- Oricur;Katonil;Merilid;Mercoral;Percapyl;ProMeran;Mercardox;Mercloran;Merculest;Neogidrin
- CBNumber:
- CB9941654
- Molecular Formula:
- C5H11ClHgN2O2
- Molecular Weight:
- 367.197
- MDL Number:
- MFCD00025457
- MOL File:
- 62-37-3.mol
| Melting point | 152-153° |
|---|---|
| Boiling point | 142°C |
| form | solid |
| FDA UNII | 99T5TWO621 |
chlormerodrin Chemical Properties,Uses,Production
Originator
Neohydrin,Lakeside,US,1952
Uses
Chlormerodrin is a sulfhydryl blocking agent; using NK cells, particularly CAR-modified NK cells, for producing induced cellular vesicles (ICVs) loaded with chemotherapeutic agent(s) for cancer therapy.
Definition
ChEBI: Chlormerodrin is urea in which one of the hydrogens is substituted by a 3-chloromercury-2-methoxyprop-1-yl group. It was formerly used as a diuretic, but more potent and less toxic drugs are now available. Its radiolabelled ((197)Hg, (203)Hg) forms were used in diagnostic aids in renal imaging and brain scans. It has a role as a diuretic and a diagnostic agent. It is an organomercury compound and a member of ureas.
Manufacturing Process
To a refluxing solution of 100 g of allyl urea and 600 ml of absolute methanol there was added with stirring a suspension of 319 g of mercuric acetate and 600 ml of absolute methanol and 60 ml of glacial acetate acid; complete solution resulted. After 6 hours of refluxing, the solution was cooled and clarified by filtration. To this solution there were added 50 g of sodium chloride and 240 ml of water. After a short time a heavy white precipitate settled out. This precipitate, which was 3-chloromercuri-2-methoxypropylurea, was filtered, washed and dried.
brand name
Mercloran (Parke-Davis); Neohydrin (Marion Merrell Dow).
Therapeutic Function
Diuretic
chlormerodrin Preparation Products And Raw materials
chlormerodrin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 10011 | 58 |
| Supplier | Advantage |
|---|---|
| SPIRO PHARMA | 55 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 58 |