Dihydromyricetin
- CAS No.
- 27200-12-0
- Chemical Name:
- Dihydromyricetin
- Synonyms
- ampeloptin;AMPELOPSIN;Two hydrogenMyricetin;vine tea extract dihydromyricetin;3,3’,4’,5,5’,7-hexahydroxy-flavanon;DihydroMyricetin, froM Myrica rubra;3,3’,4’,5,5’,7-hexahydroxy-2,3-dihydroflavanonol;2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on;3,3',4',5,5;,(2r-trans)-
- CBNumber:
- CB1670507
- Molecular Formula:
- C15H12O8
- Molecular Weight:
- 320.25
- MOL File:
- 27200-12-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2026/4/22 18:57:36
| storage temp. | -20°C |
|---|---|
| solubility | DMSO: ≥5mg/mL (warmed) |
| form | powder |
| Boiling point | 780.7±60.0 °C(Predicted) |
| Density | 1.808±0.06 g/cm3(Predicted) |
| Melting point | 239-241 °C |
| pka | 7.38±0.60(Predicted) |
| color | white to beige |
| Stability | Hygroscopic |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1 |
| InChIKey | KJXSIXMJHKAJOD-LSDHHAIUSA-N |
| SMILES | [C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O |
| LogP | 1.230 (est) |
| CAS DataBase Reference | 27200-12-0 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 29329990 |
| Storage Class | 11 - Combustible Solids |
Dihydromyricetin price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 42866 | Dihydromyricetin analytical standard | 27200-12-0 | 10MG | ₹16042.65 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D5464 | Dihydromyricetin | 27200-12-0 | 200MG | ₹5700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5464 | Dihydromyricetin | 27200-12-0 | 1G | ₹8800 | 2022-05-26 | Buy |
Dihydromyricetin Chemical Properties,Uses,Production
Description
Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.
Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities，and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).
Uses
Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.
Definition
ChEBI: (+)-dihydromyricetin is an optically active form of dihydromyricetin having (2R,3R)-configuration. It has a role as a metabolite, an antioxidant and an antineoplastic agent. It is a secondary alpha-hydroxy ketone and a dihydromyricetin. It is an enantiomer of a (-)-dihydromyricetin.
Clinical Use
Dihydromyricetin can be used as a novel anti-alcoholism drug, clinically used to treat hangovers, fever, parasitic infections and liver disease. It is currently being studied in clinical trials for its effects on glycaemic control, insulin sensitivity and insulin secretion in type 2 diabetes.
Dihydromyricetin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SETV ASRV LLP | +91-9731133411 | Telangana, India | 437 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213306 +8618374838656 | China | 988 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29819 | 58 | Inquiry |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | China | 2639 | 58 | Inquiry |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 997 | 58 | Inquiry |
| Changyi Longchang Bio-Chemical Co., LTD | +86-13256193735; +8613256193735 | China | 1044 | 58 | Inquiry |
| Hovane Phytochemicals Co., Ltd | +86-17340288373 | China | 33 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | China | 5853 | 58 | Inquiry |
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- Dihydromyricetin (DHM) is a kind of flavonoid small molecule. It can be rapidly metabolized, with no obvious toxicity.
- Jan 15，2025
- What are the properties of dihydromyricetin and what are its health benefits?
- Dihydromyricetin (DHM) is a natural flavonoid compound isolated from the traditional Chinese medicinal plant Bletilla striata.
- Dec 16，2024
- What is Ampelopsin?
- Ampelopsin, also known as dihydromyricetin and DHM, when purported as an effective ingredient in supplements and other tonics,....
- Apr 27，2022
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