2-Acetylthiophene
- CAS No.
- 88-15-3
- Chemical Name:
- 2-Acetylthiophene
- Synonyms
- Ethanone, 1-(2-thienyl)-;AKOS 91936;2-Acetylthioph;2-Acetothienone;2-Acetylthiophen;2-ACETYLTHIOLE;2-Acylthiophene;2-ACETOTHIOPHENE;-Acetylthiophene;2-ACETYLTHIOPHENE
- CBNumber:
- CB5259889
- Molecular Formula:
- C6H6OS
- Molecular Weight:
- 126.18
- MOL File:
- 88-15-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2026/1/13 11:21:33
| Melting point | 10-11 °C (lit.) |
|---|---|
| Boiling point | 214 °C (lit.) |
| Density | 1.168 g/mL at 25 °C (lit.) |
| vapor pressure | 2.7 hPa (50 °C) |
| refractive index |
n |
| Flash point | 196 °F |
| storage temp. | Store below +30°C. |
| solubility | 14g/l |
| form | Liquid |
| color | Clear pale yellow to light brown |
| Odor | at 100.00 %. sulfurous nutty hazelnut walnut |
| Odor Type | sulfurous |
| biological source | synthetic |
| Water Solubility | Insoluble in water. |
| Sensitive | Light Sensitive |
| BRN | 107910 |
| Major Application | flavors and fragrances |
| InChI | 1S/C6H6OS/c1-5(7)6-3-2-4-8-6/h2-4H,1H3 |
| InChIKey | WYJOVVXUZNRJQY-UHFFFAOYSA-N |
| SMILES | CC(=O)c1cccs1 |
| LogP | 1.250 |
| CAS DataBase Reference | 88-15-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanone, 1-(2-thienyl)-(88-15-3) |
| EPA Substance Registry System | Ethanone, 1-(2-thienyl)- (88-15-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H330-H311 | |||||||||
| Precautionary statements | P260-P264-P270-P280-P302+P352+P312-P304+P340+P310 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | T,Xi,Xn | |||||||||
| Risk Statements | 25-23/24/25-20/21/22 | |||||||||
| Safety Statements | 45-38-36/37/39-28-36 | |||||||||
| RIDADR | UN 2810 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OB6300000 | |||||||||
| F | 13 | |||||||||
| Autoignition Temperature | 265 °C DIN 51794 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Inhalation Acute Tox. 2 Oral Acute Tox. 3 Dermal |
|||||||||
| Toxicity | LD50 orally in Rabbit: 25 - 200 mg/kg LD50 dermal Rat 370 mg/kg | |||||||||
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
2-Acetylthiophene price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W503509 | 2-Acetylthiophene ≥98%, FG | 88-15-3 | 1SAMPLE-K | ₹4990.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W503509 | 2-Acetylthiophene ≥98%, FG | 88-15-3 | 250G | ₹16205.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W503509 | 2-Acetylthiophene ≥98%, FG | 88-15-3 | 1KG | ₹48755.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A22602 | 2-Acetylthiophene 98% | 88-15-3 | 25G | ₹2457.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A22602 | 2-Acetylthiophene 98% | 88-15-3 | 100G | ₹4741.35 | 2022-06-14 | Buy |
2-Acetylthiophene Chemical Properties,Uses,Production
Chemical Properties
clear colorless to slightly yellow liquid
Uses
2-Acetylthiophene(2AT) is used as an intermediate in the manufacturing of drugs like Tiamonium Iodide, Suprofan, Stepronin, Tenonitrozole, Namirotene, etc. 2AT is used as an important precursor to thiophene-2-acetic acid (T2AA) or its acid chloride (Cl) and thiophene-2-carboxylic acid (T2CA) (Cl). It is important that the process used to synthesize 2AT yields the lowest amount of 3- acetylthiophene isomer.
Safety Profile
Poison by intraperitoneal route. A flammable liquid. When heated to decomposition emits toxic fumes of SOx,.
Solubility in organics
2-Acetylthiophene is miscible at 25°C with triethylene glycol, methanol, ethanol, n-butanol, diethyl ether, dioxane, cellulose butyl ester, ethyl acetate, acetone, acetonitrile, carbon disulphide, carbon tetrachloride, nitromethane, acetic acid, thiophene, tetranaphthalene, aminobenzene, and benzene . It is immiscible with water, glycerol, ethylene glycol, decahydronaphthalene, cyclohexane, diisobutylene, 1-hexadecene, and n-heptane. When equal volumes are mixed, 2-acetylthiophene is miscible with n-heptane above 60.8°C and with ethylene glycol above 31.1°C.
[1] JOHNSON G C. Physical Properties of 2-Acetylthiophene[J]. Journal of the American Chemical Society, 1947, 69 1: 150-152. DOI:10.1021/ja01193a040.
Purification Methods
Fractionally distil the thiophene through a 12-plate column, and fraction b 77o/4mm is collected. Also wet the acetylthiophene in order to remove and free thiophene which forms an azeotrope with H2O, b 68o. Store it in a brown bottle, and the clear colourless liquid remains thus for extended periods. [Kosak & Hartough Org Synth Coll Vol III 14 1955, Hartough & Kosak J Am Chem Soc 69 3093 1947.] The red 4-nitrophenylhydrazone crystallises from EtOH with m 181-182o. [Beilstein 17/9 V 387.]
2-Acetylthiophene Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ANJI BIOSCIENCES | +91-9000100077 | Hyderabad, India | 429 | 58 | Inquiry |
| Seema Finechem Industry LLP | +91-8451840941 | NaviMumbai, India | 43 | 58 | Inquiry |
| TRC FINE CHEMS | +91-7400278327 +91-8097105248 | Mumbai, India | 73 | 58 | Inquiry |
| Sarex Overseas | +91-9920438667 | Mumbai, India | 57 | 58 | Inquiry |
| Molkem Chemicals | +91-917228022464 +91-7228022464 | Ahmedabad, India | 138 | 58 | Inquiry |
| Zuhhad international | +91-8454840801 | Mumbai, India | 21 | 58 | Inquiry |
| VINEET LABORATORIES LIMITED | +91-9642200049 | Telangana, India | 69 | 58 | Inquiry |
| BMS Chemie | +91-9712927455 +91-9825027451 | Gujarat, India | 8 | 58 | Inquiry |
| Aventus Labs | +91-7021872517 +91-9324342304 | Maharashtra, India | 168 | 58 | Inquiry |
| Sri Neelima Laboratories | +91-7981733602 +91-9849736989 | Telangana, India | 205 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ANJI BIOSCIENCES | 58 |
| Seema Finechem Industry LLP | 58 |
| TRC FINE CHEMS | 58 |
| Sarex Overseas | 58 |
| Molkem Chemicals | 58 |
| Zuhhad international | 58 |
| VINEET LABORATORIES LIMITED | 58 |
| BMS Chemie | 58 |
| Aventus Labs | 58 |
| Sri Neelima Laboratories | 58 |
Related Qustion
- Q:What is 2-Acetylthiophene used for?
- A:
- Nov 25，2025
88-15-3(2-Acetylthiophene)Related Search:
1of4
chevron_right