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Dihydrocyclosporin a

Dihydrocyclosporin a Structure
CAS No.
59865-15-5
Chemical Name:
Dihydrocyclosporin a
Synonyms
CS-2523;Cyclosporin EP B;Dihydrocyclosporin;Capecitabine Imp.G;dihyroyclosporine A;Dihydrocyclosporin a;Dihydrocyclosporine A;Cyclosporin Impurity 10;Cyclosporine Impurity 10;Ciclosporin EP impurity B
CBNumber:
CB5352728
Molecular Formula:
C62H113N11O12
Molecular Weight:
1204.63
MOL File:
59865-15-5.mol
MSDS File:
SDS
Modify Date:
2026/9/12 18:53:30

Dihydrocyclosporin a Properties

Melting point 120-125C
Boiling point 1285.3±65.0 °C(Predicted)
Density 1.012±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka 13.33±0.70(Predicted)
form Solid
color White
InChIKey TYFOVYYNQGNDKH-AAJDKDKZNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H350-H302-H362
Precautionary statements  P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313

Dihydrocyclosporin a price

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Dihydrocyclosporin a Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Dihydrocyclosporin A (DHCsA-d) is cyclosporine A (CsA) derivative. DHCsA-d significantly inhibited promastigotes and intracellular amastigotes, but it is highly cytotoxic.

Uses

Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections.

Side effects

Dihydrocyclosporine A has no obvious nephrotoxic effect, but it exhibits hepatotoxic effects, often leading to hypertension.

Dihydrocyclosporin a Preparation Products And Raw materials

Raw materials

Preparation Products

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Dihydrocyclosporin a Spectrum

59865-15-5(Dihydrocyclosporin a)Related Search:

Dihydrocyclosporin (3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] (3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) 6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A Cyclosporin A Dihydro IMpurity Dihydrocyclosporine A Cyclosporin Impurity 10 Dihydrocyclosporin A reference Dihydrocyclosporine A/6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A CS-2523 Cyclosporin Impurity 10(Dihydrocyclosporin A) Cyclosporin A,6-[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoic acid]- Capecitabine Imp.G Cyclosporine Impurity 10 Ciclosporin EP impurity B Cyclosporin Impurity 10(Dihydrocyclosporin A)(Ciclosporin EP Impurity B) Ciclosporin EP Impurity B (Dihydrocyclosporin A) Cyclosporin EP B (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone Dihydrocyclosporin A, 10 mM in DMSO dihyroyclosporine A Dihydrocyclosporin a 59865-15-5 C62H113N11O12 Intermediates & Fine Chemicals Peptides Pharmaceuticals