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Dihydrocyclosporin a

CAS No.
59865-15-5
Chemical Name:
Dihydrocyclosporin a
Synonyms
CS-2523;Cyclosporin EP B;Dihydrocyclosporin;Capecitabine Imp.G;dihyroyclosporine A;Dihydrocyclosporin a;Dihydrocyclosporine A;Cyclosporin Impurity 10;Cyclosporine Impurity 10;Ciclosporin EP impurity B
CBNumber:
CB5352728
Molecular Formula:
C62H113N11O12
Molecular Weight:
1204.63
MDL Number:
MFCD08458303
MOL File:
59865-15-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:30

Dihydrocyclosporin a Properties

Melting point 120-125C
Boiling point 1285.3±65.0 °C(Predicted)
Density 1.012±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka 13.33±0.70(Predicted)
form Solid
color White
InChIKey TYFOVYYNQGNDKH-AAJDKDKZNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H350-H302-H362
Precautionary statements  P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313

Dihydrocyclosporin a price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological D3801-01 Dihydrocyclosporin A ~98%(HPLC) 59865-15-5 1mg $362 2026-06-03 Buy
TRC TRC-D448865-5MG Dihydro Cyclosporin A >95%(HPLC) 59865-15-5 5mg $209 2026-06-03 Buy
TRC TRC-D448865-50MG Dihydro Cyclosporin A >95%(HPLC) 59865-15-5 50mg $1273 2026-06-03 Buy
TRC TRC-D448865-10MG Dihydro Cyclosporin A >95%(HPLC) 59865-15-5 10mg $309 2026-06-03 Buy
Usbiological 009720 Dihydro Cyclosporin A 59865-15-5 10mg $475 2026-06-03 Buy
Product number Packaging Price Buy
D3801-01 1mg $362 Buy
TRC-D448865-5MG 5mg $209 Buy
TRC-D448865-50MG 50mg $1273 Buy
TRC-D448865-10MG 10mg $309 Buy
009720 10mg $475 Buy

Dihydrocyclosporin a Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

Dihydrocyclosporin A (DHCsA-d) is cyclosporine A (CsA) derivative. DHCsA-d significantly inhibited promastigotes and intracellular amastigotes, but it is highly cytotoxic.

Uses

Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections.

Uses

A Cyclosporin A (C988900) analog, an immunosuppressant.

Side effects

Dihydrocyclosporine A has no obvious nephrotoxic effect, but it exhibits hepatotoxic effects, often leading to hypertension.

59865-13-3
59865-15-5
Synthesis of Dihydrocyclosporin a from Cyclosporin A

Dihydrocyclosporin a Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 107)
Supplier Tel Email Country ProdList Advantage
Hefei fuya biotechnology co. LTD 18096409024 sales02@foreversyn.com China 1933 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 4999 50
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Hangzhou J&H Chemical Co., Ltd. 0571-87396432 sales@jhechem.com China 14878 59

View Latest Price from Dihydrocyclosporin a manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dihydrocyclosporin A pictures 2026-05-11 Dihydrocyclosporin A
59865-15-5
$129.00-470.00 99.96% 10g TargetMol Chemicals Inc.
Dihydrocyclosporin A pictures 2026-02-27 Dihydrocyclosporin A
59865-15-5
10mg 95% HPLC 100g Shenzhen Excellent Biomedical Technology Co.,Ltd.
Ciclosporin EP Impurity B pictures 2025-12-16 Ciclosporin EP Impurity B
59865-15-5
10mg 95%+ 100000 Moxin Chemicals

Dihydrocyclosporin a Spectrum

Dihydrocyclosporin (3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] (3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) 6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A Cyclosporin A Dihydro IMpurity Dihydrocyclosporine A Cyclosporin Impurity 10 Dihydrocyclosporin A reference Dihydrocyclosporine A/6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A CS-2523 Cyclosporin Impurity 10(Dihydrocyclosporin A) Cyclosporin A,6-[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoic acid]- Capecitabine Imp.G Cyclosporine Impurity 10 Ciclosporin EP impurity B Cyclosporin Impurity 10(Dihydrocyclosporin A)(Ciclosporin EP Impurity B) Ciclosporin EP Impurity B (Dihydrocyclosporin A) Cyclosporin EP B (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone Dihydrocyclosporin A, 10 mM in DMSO dihyroyclosporine A Dihydrocyclosporin a 59865-15-5 C62H113N11O12 Intermediates & Fine Chemicals Peptides Pharmaceuticals