ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Estrogen and progestin drugs >17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether Structure
CAS No.
72-33-3
Chemical Name:
17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether
Synonyms
33355;EE3ME;d-MVE;sc4725;RS 1044;Devocin;Norquen;Ovastol;SC 4725;MESTRANOL
CBNumber:
CB7426942
Molecular Formula:
C21H26O2
Molecular Weight:
310.43
MOL File:
72-33-3.mol
Modify Date:
2023/4/23 13:52:06

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether Properties

Melting point 153-155 °C(lit.)
alpha +2~+8°(D/20℃)(c=1, 1,4-dioxane)
Boiling point 390.58°C (rough estimate)
Density 1.0865 (rough estimate)
refractive index 1.4900 (estimate)
storage temp. Sealed in dry,2-8°C
solubility Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka 13.10±0.40(Predicted)
optical activity [α]15/D +3°, c = 2 in dioxane
Merck 5917
BRN 2625905
CAS DataBase Reference 72-33-3(CAS DataBase Reference)
NIST Chemistry Reference Mestranol(72-33-3)
EPA Substance Registry System Mestranol (72-33-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H315-H319-H351
Precautionary statements  P201-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xn
Risk Statements  36/37/38-40-48-68
Safety Statements  22-26-36/37/39-45-36/37
WGK Germany  3
RTECS  RC8960000
HS Code  29372900
Toxicity LD50 oral in rat: > 10gm/kg
NFPA 704
0
1 0

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 855871 Mestranol 99% 72-33-3 500MG ₹4643.93 2022-06-14 Buy
TCI Chemicals (India) M0728 Mestranol 72-33-3 5G ₹15600 2022-05-26 Buy
Product number Packaging Price Buy
855871 500MG ₹4643.93 Buy
M0728 5G ₹15600 Buy

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

Mestranol is an orally active estrogenic steroid. It was the estrogen used in many of the first oral contraceptives

Definition

ChEBI: A terminal acetylenic compound that is (17alpha)-17-ethynylestra-1(10),2,4-triene substituted by a methoxy group at position 3 and a hydroxy group at position 17.

Safety Profile

Confirmed carcinogen with experimental. neoplastigenic, tumorigenic, and teratogenic data. Moderately toxic by subcutaneous route. Human reproductive effects by ingestion: changes in ovaries and fallopian tubes, ferthty effects. Experimental reproductive effects. Mutation data reported. An FDA proprietary drug. A steroid used in oral contraceptives. When heated to decomposition it emits acrid smoke and irritating fumes.

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 190)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
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Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 27078 58 Inquiry
Ethynylestradiol 3-methyl ether,97% 17alpha-19-Norpregna-1,3,5(10)-trien-20-yn MESTRANOL 19-Nor-17alpha-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy- 19-nor-17α-pregna-1,3,5(10)-trien-20-yn-17-ol,3-methoxy- 19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, (17alpha)- 3,17-beta-Dihydroxy-17-alpha-ethynyl-1,3,5(10)-estratriene-3-methyl ether 3,17-beta-dihydroxy-17-alpha-ethynyl-1,3,5(10)-estratriene-3-methylether 33355 3-methoxy-17a-ethynyl-1,3,5(10)-estratriene-17b-ol 3-methoxy-17-alpha-19-norpregna-1,3,5(10)-trien-20-yn-17-ol 3-methoxy-17-alpha-ethinylestradiol 3-Methoxy-17alpha-ethinylestradiol 3-methoxy-17-alpha-ethinyloestradiol 3-Methoxy-17alpha-ethinyloestradiol 3-methoxy-19-nor-17α-pregna-1,2,5(10)-triene-20-yn-17-ol 3-Methoxyethynylestradiol 3-methoxyethynyloestradiol 3-Methylethynylestradiol 3-methylethynyloestradiol 3-O-Methylethynylestradiol 5(10)-trien-17-beta-ol,17-alpha-ethynyl-3-methoxy-estra-3 5(10)-trien-20-yn-17-ol,3-methoxy-17-alpha-19-norpregna-3 8027 C. B. component of Norinyl component of Norquen component of Ortho-Novum component of Ovulen Compound 33355 compound33355 delta-MVE sc4725 ETHYNYLESTRADIOL 3-METHYL ETHER ETHINYLESTRADIOL METHYL ETHER 3-METHOXY-17ALPHA-ETHYNYLESTRADIOL (8R,9S,13S,14S,17R)-17-ETHYNYL-3-METHOXY-13-METHYL-7,8,9,11,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHREN-17-OL 17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-methyl ether 17A-ETHYNYLESTRADIOL 3-METHYLTHER (17A)-3-METHOXY-19-NORPREGMA-1,3,5(10)-TRIEN-20-YN-17-OL 17-ALPHA-ETHINYL-OESTRADIOL-3-METHYL ETHER 17ALPHA-ETHYNYL-1,3,5(10)-ESTRATRIENE-3,17BETA-DIOL 3-METHYL ETHER 17ALPHA-ETHYNYLESTRADIOL 3-METHYL ETHER 1,3,5(10)-ESTRATRIEN-17-ALPHA-ETHYNYL-3,17-BETA-DIOL 3-METHYL ETHER 3-Methoxy-19-nor-17α-pregna-1,3,5[10]-trien-20-yn-17-ol 17a-Ethynyl-3-methoxy-17b-hydroxy-1,3,5(10)-estratriene 3-Methoxy-17a-ethynylestradiol (17a)-3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol Menophase 17α-ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-methyl ether 17a-Ethinylestradiol 3-methyl ether 17a-Ethynyl-3-methoxy-1,3,5(10)-estratrien-17b-ol 17a-Ethynyl-3-methoxy-17b-hydroxy-D1,3,5(10)-estratriene 17a-Ethynylestradiol methyl ether 17-Ethynyl-3-methoxy-1,3,5(10)-estratrien-17b-o1 17-Ethynyl-3-methoxyestra-1,3,5(10)-trien-17b-ol 19-Nor-17a-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy- (6CI, 8CI) MESTRANOL, VETRANAL 100MG MESTRANOL 98+%