Buspirone hydrochloride
- CAS No.
- 33386-08-2
- Chemical Name:
- Buspirone hydrochloride
- Synonyms
- BUSPIRONE HCL;Narol;bespar;axoren;travin;Ansial;censpar;lucelan;Ansiced;buspinol
- CBNumber:
- CB8367136
- Molecular Formula:
- C21H32ClN5O2
- Molecular Weight:
- 421.96
- MOL File:
- 33386-08-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2026/4/22 18:57:36
| Melting point | 201.5-202.50C |
|---|---|
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | Freely soluble in water and in methanol, practically insoluble in acetone. |
| form | Solid |
| color | White to off-white |
| Water Solubility | Soluble in methanol (50 mg/ml), water (partly), DMSO (100 mM). |
| Major Application | pharmaceutical |
| InChI | InChI=1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H |
| InChIKey | RICLFGYGYQXUFH-UHFFFAOYSA-N |
| SMILES | C12(CCCC1)CC(N(CCCCN1CCN(C3=NC=CC=N3)CC1)C(=O)C2)=O.Cl |
| CAS DataBase Reference | 33386-08-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T,Xn,F | |||||||||
| Risk Statements | 25-36/37/38-20/21/22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 45-36-26-36/37-16 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CL9915000 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29335995 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral | |||||||||
| Toxicity | LD50 i.p. in rats: 136 mg/kg (Allen) | |||||||||
| NFPA 704 |
|
Buspirone hydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B7148 | Buspirone hydrochloride | 33386-08-2 | 1G | ₹8356.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1917 | Buspirone hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 33386-08-2 | 500MG | ₹31652.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B7148 | Buspirone hydrochloride | 33386-08-2 | 5G | ₹27495.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B-054 | Buspirone hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 33386-08-2 | 1ML | ₹9323.3 | 2022-06-14 | Buy |
Buspirone hydrochloride Chemical Properties,Uses,Production
Description
Buspirone hydrochloride is an anxiolytic agent indicated for the management of anxiety disorders with or without accompanying depression. In contrast to the benzodiazepines, buspirone does not interact with alcohol, and lacks sedative, anticonvulsant, and muscle relaxant effects, and abuse potential.
Chemical Properties
White Solid
Uses
Non-benzodiazepine anxiolitic; 5-hydroxytryptamine (5-HT1) receptor agonist.
Definition
ChEBI: A hydrochloride salt resulting from the reaction of equimolar amounts of buspirone and hydrogen chloride.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Biological Activity
Classic 5-HT 1A partial agonist with relatively high affinity (K i = 9.3 - 29.5 nM). A clinically effective anxiolytic.
Buspirone hydrochloride Preparation Products And Raw materials
Raw materials
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Global( 307)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| KARPSCHEM LABORATORIES | +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Medilux Laboratories Pvt Ltd | +91-7292409991 +91-9819666688 | Madhya Pradesh, India | 102 | 58 | Inquiry |
| Unimark Remedies Ltd | +91-2267304120 | Maharashtra, India | 48 | 58 | Inquiry |
| SRINI PHARMACEUTICALS PVT LTD | +91-7093200121 | Telangana, India | 204 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6202 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6514 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| CLEANCHEM LABORATORIES LLP | +91 98921 69560 | New Delhi, India | 325 | 58 | Inquiry |
33386-08-2(Buspirone hydrochloride)Related Search:
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Buspirone hydrochloride,N-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride
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8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-9-dione
axoren
bespar
buspinol
buspironechloridate
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N-[4-(4-[2-PYRIMIDINYL]-1-PIPERAZINYL)BUTYL]-8-AZASPIRO[4,5]DECANE-7,9-DIONE HYDROCHLORIDE
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lucelan
mj9022-1
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Ansial
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Buspirone Hydrochloride
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8-[4-[4-(2-pyrimidinyl)-1-piperazin-1-iumyl]butyl]-8-azaspiro[4.5]decane-7,9-dione
Narol
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8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione, hydrochloride (1:1)
Buspirone Hydrochloride
8-[4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]- decane-7,9-dione hydrochloride
Buspirone hydrochloride in Methanol
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BUSPIRONE HCL
33386-08-2
C21H32ClN5O2
C21H31N5O2HCl
C21H31N5O2xHCl
C21H32N5O2
42196
Inhibitors