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Estradiol benzoate

Estradiol benzoate Structure
CAS No.
50-50-0
Chemical Name:
Estradiol benzoate
Synonyms
ODB;MEE;Oestradiol benzoate;EBZ;folone;17β-Estradiol benzoate;(17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;ESTON-B;diogynb;Graafina
CBNumber:
CB9131644
Molecular Formula:
C25H28O3
Molecular Weight:
376.5
MOL File:
50-50-0.mol
MSDS File:
SDS
Modify Date:
2024/3/27 16:40:14

Estradiol benzoate Properties

Melting point 191-198 °C(lit.)
alpha D25 +58 to +63° (c = 2 in dioxane)
Boiling point 465.03°C (rough estimate)
Density 1.0493 (rough estimate)
refractive index 1.5460 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol.
pka 15.06±0.40(Predicted)
color White
Water Solubility 0.4mg/L(25 ºC)
Merck 3703
BRN 3107526
CAS DataBase Reference 50-50-0(CAS DataBase Reference)
NIST Chemistry Reference Estradiol benzoate(50-50-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H351-H360FD
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  T
Risk Statements  60-61-40
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  KG4050000
8
HS Code  29372319

Estradiol benzoate price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) E8515 β-Estradiol 3-benzoate ≥97% 50-50-0 200MG ₹2662.95 2022-06-14 Buy
Sigma-Aldrich(India) E8515 β-Estradiol 3-benzoate ≥97% 50-50-0 1G ₹6971.3 2022-06-14 Buy
Sigma-Aldrich(India) PHR2858 Estradiol Benzoate certified reference material, pharmaceutical secondary standard 50-50-0 500MG ₹26369.7 2022-06-14 Buy
Sigma-Aldrich(India) E8515 β-Estradiol 3-benzoate ≥97% 50-50-0 5G ₹23923.25 2022-06-14 Buy
Sigma-Aldrich(India) 46552 β-Estradiol 3-benzoate VETRANAL?, analytical standard 50-50-0 10MG ₹6473.35 2022-06-14 Buy
Product number Packaging Price Buy
E8515 200MG ₹2662.95 Buy
E8515 1G ₹6971.3 Buy
PHR2858 500MG ₹26369.7 Buy
E8515 5G ₹23923.25 Buy
46552 10MG ₹6473.35 Buy

Estradiol benzoate Chemical Properties,Uses,Production

Chemical Properties

White solid

Definition

ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.

Clinical Use

Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.

Estradiol benzoate Preparation Products And Raw materials

Global( 429)Suppliers
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Asg Biochem Pvt. Ltd +91-9650436669 +91-9650436669 New Delhi, India 25 58 Inquiry
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Sanjivani Pharma 08048371780Ext 182 Gujarat, India 8 58 Inquiry
ASG Biochem 09958992614 Delhi, India 1 58 Inquiry
Queens Pharmaceuticals 07267768980 Mumbai, India 1 58 Inquiry
1,3,5(10)-Estratriene-3,17-diol-3-benzoate 1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate 1,3,5(10)-oestratriene-3,17-beta-diol3-benzoate BETA-ESTRADIOL 3-BENZOATE BETA-ESTRADIOL BENZOATE B-ESTRADIOL-3-BENZOATE 17beta-Estradiol monobenzoate 17-beta-estradiolmonobenzoate 17-beta-Oestradiol 3-benzoate 17-beta-oestradiol3-benzoate 17-Hydroxyestra-1(10),2,4-trien-3-yl benzoate beta-oestradiolbenzoate De Graafina degraafina Diffollisterol 3,17b-dihydroxy-1,3,5(10)-estratriene 3-benzoate 3-Benzoyloxy-17β-hydroxyestra-1,3,5(10)-triene Agofollin Depot Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-benzoate Estradiol, 3-benzoate (8CI) Diffolistedrol ESTRADIOLBENZOATE,POWDER ESTRADIOL BENZATE 1,3,5(10)-Estratriene-3,17β-diol 3-benzoate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-benzoate, 3-Benzoyloxy-17β-estrol [(8R,9S,13S,14S,17S)-17-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate 17β-(Benzoyloxy)estra-1,3,5(10)-trien-3-ol 17β-Estradiol 17-benzoate 17BETA-ESTRADIOL 3-BENZOATE VETRANAL250 BETA-ESTRADIOL-3-BENZOATE-CARC. Estra-1,3,5(10)-triene-3,17β-diol 3-benzoate 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-benzoate 3-Benzoate 17β-estradiol3-benzoate 3-(benzoyloxy)estra-1,3,5(10)-trien-17β-ol Benovocylin Benzestrofol Benzhormovarine Benzoate d'oestradiol benzoated’oestradiol Benzoestrofol Benzoestrofol difolliculin Benzofoline Benzogynestryl Benzo-Gynoestryl Benzoic acid estradiol benzoicacidestradiol Benztrone beta-Oestradiol 3-benzoate beta-Oestradiol benzoate beta-oestradiol3-benzoate Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-benzoate estra-1,3,5(10)-triene-3,17-diol(17-beta)-3-benzoate Estradiol monobenzoate Estradiol, 3-benzoate estradiol,3-benzoate Estradiol-17beta 3-benzoate Estradiol-17beta benzoate estradiol-17-beta-3-benzoate