KDOAM-25

 化学構造式
2230731-99-2
CAS番号.
2230731-99-2
化学名:
别名:
英語名:
KDOAM-25
英語别名:
KDOAM-25;KDOAM 25,KDOAM25;KDOAM-25 trihydrochloride;4-Pyridinecarboxamide, 2-[[[2-[[2-(dimethylamino)ethyl]ethylamino]-2-oxoethyl]amino]methyl]-
CBNumber:
CB03339897
化学式:
C15H25N5O2
分子量:
307.39
MOL File:
2230731-99-2.mol

KDOAM-25 物理性質

沸点 :
478.6±45.0 °C(Predicted)
比重(密度) :
1.137±0.06 g/cm3(Predicted)
貯蔵温度 :
-20°C
酸解離定数(Pka):
15.03±0.50(Predicted)

安全性情報

KDOAM-25 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

KDOAM-25 化学特性,用途語,生産方法

Biochem/physiol Actions

KDOAM25 is a selective inihbitor of the KDM5 family histone demethylases JARID1A, JARID1B, JARID1C and JARID1D with IC50 values < 60 nM. JARID1A and JARID1B are independently overexpressed in some cancers with JARID1B (KDM5B, PLU1) also identified as a potential oncogene, a repressor of tumour repressor genes. JARID1C (KDM5C) and JARID1D (KDM5D) are located on the X- and Y-chromosomes respectively. KDOAM25′s closest off-target is JMJD2C (selectivity >400 fold). It shows no activity on other tested 2-OG family members, including FIH, NO66, MINA53 and PHD2. KDOAM25 is active in cells.

KDOAM-25 上流と下流の製品情報

原材料

準備製品


KDOAM-25 生産企業

Global( 13)Suppliers
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TargetMol Chemicals Inc.
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Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
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Sigma-Aldrich 021-61415566 800-8193336
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DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9414 58
Shanghai hongqu biomedical technology co. LTD 88888888888
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ShangHai ChuanQian Chemcial Technique Centre 15869524721
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cjbscvictory 13348960310 13348960310
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Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
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TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24131 58

  • 2230731-99-2
  • KDOAM-25
  • 4-Pyridinecarboxamide, 2-[[[2-[[2-(dimethylamino)ethyl]ethylamino]-2-oxoethyl]amino]methyl]-
  • KDOAM-25 trihydrochloride
  • KDOAM 25,KDOAM25
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