ベノキサプロフェン 化学特性,用途語,生産方法
効能
鎮痛薬, 抗炎症薬
使用
A non-steroidal anti-inflammatory ophthalmic agent.
定義
ChEBI: A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group. It was used as a non-steroidal anti-inflammatory drug until 1982 when it was withdrawn from the market due to adverse side-effects inc
uding liver necrosis, photosensitivity, and carcinogenicity in animals.
世界保健機関(WHO)
Benoxaprofen, a nonsteroidal antiinflammatory agent, was
introduced in 1980 for the treatment of rheumatic disorders. Following reports of
serious adverse effects, some of which were fatal, it was withdrawn in several
countries prior to worldwide withdrawal by the manufacturer in 1982.
安全性プロファイル
Poison by ingestion, subcutaneous, and intraperitoneal routes. Moderately toxic to humans by ingestion.Human systemic effects by ingestion: jaundice and gynecomastia (excessive development of the male mammary glands), changes in kidney tubules, decreased
ベノキサプロフェン 上流と下流の製品情報
原材料
準備製品