タリペキソール

タリペキソール 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

タリペキソール 化学特性,用途語,生産方法

効能

パーキンソン病治療薬, ドパミンD2受容体作動薬

説明

Domin was launched in Japan for Parkinson's disease. The compound is readily accessible in two steps from I-allylhexahydro-4H-azepin4-one. Its antiparkinson activity resides in the fact that talipexole is a selective agonist for presynaptic dopamine D₂ receptors with no D₁ receptor activity. It is a clonidine-like α₂-adrenoreptor agonist and has fewer GI side effects than bromocriptine the most widely used dopamine angonist. Also it is 70 times more potent than bromocriptine and has a more rapid onset of action. In addition to its anti-tremor activity there was a sedative effect but no emesis. The latter probably a result of talipexole's 5-HT₃ receptor antagonistic activity. Its metabolites have no biological activity, there was no development of tolerence and its effect could be enhanced by L-dopa.

Originator

Boehringer Ingelheim (Germany)

brand name

Domin

タリペキソール 上流と下流の製品情報

原材料

準備製品

タリペキソール 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2127	70
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
LETOPHARM LIMITED	+86-21-5821 5861	sales@letopharm.com	China	2384	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29797	68

101626-70-4(タリペキソール)キーワード:

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• 101626-70-4
• TALIPEXOLE
• 5，6，7，8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4，5-d]azepin-2-amine
• Domin
• 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine
• 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine
• Talipexol
• Talipexol [spanish]
• Talipexolum
• Talipexolum [latin]
• 6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
• TALIPEXOLE USP/EP/BP
• 4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-
• 6-アリル-2-アミノ-5,6,7,8-テトラヒドロ-4H-チアゾロ[4,5-d]アゼピン
• タリペキソール
• 6-アリル-5,6,7,8-テトラヒドロ-4H-チアゾロ[4,5-d]アゼピン-2-アミン
• 5,6,7,8-テトラヒドロ-6-(2-プロペニル)-4H-チアゾロ[4,5-d]アゼピン-2-アミン
• 2-アミノ-6-アリル-5,6,7,8-テトラヒドロ-4H-チアゾロ[4,5-d]アゼピン
• 6-(プロパ-2-エン-1-イル)-4H,5H,6H,7H,8H-[1,3]チアゾロ[4,5-d]アゼピン-2-アミン
• Ｐａｒｋｉｎｓｏｎ病治療薬
• αアドレナリン作動薬
• ドーパミン作動薬