4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩
4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩 物理性質
- 融点 :
- 241-243 °C
- 貯蔵温度 :
- -20°C
- BRN :
- 8024554
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H318 |
重篤な眼の損傷 |
眼に対する重篤な損傷性/眼刺激 性 |
1 |
危険 |
|
P280, P305+P351+P338, P310 |
|
| 注意書き |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
| P305+P351+P338 |
眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
|
4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩 価格
もっと(2)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
N8010 |
protease inhibitor and substrate
4-Nitrophenyl 4-guanidinobenzoate hydrochloride protease inhibitor and substrate |
19135-17-2 |
500mg |
￥45700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
N8010 |
protease inhibitor and substrate
4-Nitrophenyl 4-guanidinobenzoate hydrochloride protease inhibitor and substrate |
19135-17-2 |
1g |
￥81600 |
2024-03-01 |
購入 |
4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩 化学特性,用途語,生産方法
使用
4-Nitrophenyl 4-guanidinobenzoate hydrochloride has been used:
- as a substrate for trypsin for active site titration experiments
- for pre-treating of mosquito eggs in the interplasmid transposition assay
- as a component of isotonic buffer to moisten filter paper for mosquito embryo collection
一般的な説明
4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) is a trypsin substrate. It is more water-soluble than 4-methylumbelliferyl 4-guanidinobenzoate and is preferred in spectrophotometric assay.
Biochem/physiol Actions
4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) inhibits phenoloxidase enzyme and delays embryo chorionic membrane hardening.
参考文献
[1] BHUMI PATEL . L. donovani XPRT: Molecular characterization and evaluation of inhibitors[J]. Biochimica et biophysica acta. Proteins and proteomics, 2018, 1866 3: Pages 426-441. DOI:
10.1016/j.bbapap.2017.12.002.
[2] FRANK S. STEVEN Margaret M G. Studies on the Molecular Mechanism of Mersalyl and 4-Aminophenylmercuric Acetate Re-activation of Trypsin-Thiol Complexes[J]. The FEBS journal, 1980, 109 2: 567-573. DOI:
10.1111/j.1432-1033.1980.tb04829.x.
[3] YING-YING HE . Isolation, expression and characterization of a novel dual serine protease inhibitor, OH-TCI, from king cobra venom[J]. Peptides, 2008, 29 10: Pages 1692-1699. DOI:
10.1016/j.peptides.2008.05.025.
[4] J.A. SCHIFFERLI G. S. A simple two-step procedure for the preparation of the first component of human complement (C1) in its native form[J]. Journal of immunological methods, 1985, 76 2: Pages 283-288. DOI:
10.1016/0022-1759(85)90305-9.
[5] J. M. KAMINSKI. Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates[J]. Journal of Medicinal Chemistry, 1986, 29 4: 514-519. DOI:
10.1021/jm00154a015.
4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩 上流と下流の製品情報
原材料
準備製品
4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩 生産企業
Global( 14)Suppliers
19135-17-2(4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩)キーワード:
- 19135-17-2
- 4-GUANIDINOBENZOIC ACID 4-NITROPHENYL-ESTER HYDROCHLORIDE
- 4-NITROPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE
- NPGB
- PNPGB
- P-NITROPHENYL P'-GUANIDINOBENZOATE HYDROCHLORIDE
- P-NITROPHENYL-P-GUANIDINOBENZOATE HYDROCHLORIDE
- P'-GUANIDINOBENZOIC ACID P-NITROPHENYL ESTER HYDROCHLORIDE
- Nsc163801
- 4-nitrophenyl 4-[(aminoiminomethyl)amino]benzoate monohydrochloride
- P-NITROPHENYL P'-GUANIDINOBENZOATE HCL
- 4-NITROPHENYL 4-GUANIDINOBENZOATE &
- p-nitrophenyl-p'-guanidinobenzoateHClcrystalline
- p-Nitrophenyl-p'-guanidinobenzoatehydrochloridecrystalline
- Benzoic acid, 4-(aminoiminomethyl)amino-, 4-nitrophenyl ester, monohydrochloride
- 4-Guanidinobenzoic acid 4-nitrophenylester hydrochloride, NPGB, pNPGB
- (4-nitrophenyl)4-(diaminomethylideneamino)benzoate,hydrochloride
- 4-Nitrophenyl 4-guanidinobenzoate hydrochloride protease inhibitor and substrate
- 4-[(アミノイミノメチル)アミノ]安息香酸4-ニトロフェニル・塩酸塩