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NPGB

NPGB 구조식 이미지

카스 번호:: 19135-17-2

상품명:: NPGB

동의어(영문):: NPGB;PNPGB;Nsc163801;P-NITROPHENYL P'-GUANIDINOBENZOATE HCL;4-NITROPHENYL 4-GUANIDINOBENZOATE &;4-NITROPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE;P-NITROPHENYL-P-GUANIDINOBENZOATE HYDROCHLORIDE;P-NITROPHENYL P'-GUANIDINOBENZOATE HYDROCHLORIDE;p-nitrophenyl-p'-guanidinobenzoateHClcrystalline;4-GUANIDINOBENZOIC ACID 4-NITROPHENYL-ESTER HYDROCHLORIDE

CBNumber:: CB6287205

분자식:: C14H13ClN4O4

포뮬러 무게:: 336.73

MOL 파일:: 19135-17-2.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 14

NPGB 속성

녹는점: 241-243 °C

저장 조건: -20°C

BRN: 8024554

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xi
위험 카페고리 넘버	36
안전지침서	26
WGK 독일	3
F 고인화성물질	8-10

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H318	눈에 심한 손상을 일으킴	심한 눈 손상 또는 자극성 물질	구분 1	위험		P280, P305+P351+P338, P310

예방조치문구:

P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

NPGB C화학적 특성, 용도, 생산

용도

4-Nitrophenyl 4-guanidinobenzoate hydrochloride has been used:

as a substrate for trypsin for active site titration experiments
for pre-treating of mosquito eggs in the interplasmid transposition assay
as a component of isotonic buffer to moisten filter paper for mosquito embryo collection

일반 설명

4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) is a trypsin substrate. It is more water-soluble than 4-methylumbelliferyl 4-guanidinobenzoate and is preferred in spectrophotometric assay.

Biochem/physiol Actions

4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) inhibits phenoloxidase enzyme and delays embryo chorionic membrane hardening.

참고 문헌

[1] BHUMI PATEL . L. donovani XPRT: Molecular characterization and evaluation of inhibitors[J]. Biochimica et biophysica acta. Proteins and proteomics, 2018, 1866 3: Pages 426-441. DOI:10.1016/j.bbapap.2017.12.002.
[2] FRANK S. STEVEN Margaret M G. Studies on the Molecular Mechanism of Mersalyl and 4-Aminophenylmercuric Acetate Re-activation of Trypsin-Thiol Complexes[J]. The FEBS journal, 1980, 109 2: 567-573. DOI:10.1111/j.1432-1033.1980.tb04829.x.
[3] YING-YING HE . Isolation, expression and characterization of a novel dual serine protease inhibitor, OH-TCI, from king cobra venom[J]. Peptides, 2008, 29 10: Pages 1692-1699. DOI:10.1016/j.peptides.2008.05.025.
[4] J.A. SCHIFFERLI G. S. A simple two-step procedure for the preparation of the first component of human complement (C1) in its native form[J]. Journal of immunological methods, 1985, 76 2: Pages 283-288. DOI:10.1016/0022-1759(85)90305-9.
[5] J. M. KAMINSKI. Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates[J]. Journal of Medicinal Chemistry, 1986, 29 4: 514-519. DOI:10.1021/jm00154a015.

NPGB 준비 용품 및 원자재

원자재

준비 용품

NPGB 공급 업체

글로벌( 14)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Beijing Haite lesk Technology Co., Ltd	15210893940; 15116916250	chemistryliu@163.com	China	7327	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Shaanxi Dideu Newmaterial Co., Ltd.	029-63373950 15353716720	1052@dideu.com	China	10007	58
Shanghai Yingxin laboratory equipment Co., Ltd	021-021-59178156 15300768757	359382369@qq.com	China	10680	58
Shanghai Guchen Biotechnology Co., LTD	021-34675735 19147740836	1986399151@qq.com	China	9849	58

NPGB 관련 검색:

페닐 벤조산염 4-구아니디노벤조산 염화수소산염 4-(Methylamino)benzoic acid 4-AMINOBENZOIC ACID HCL 4-Benzyloxyaniline hydrochloride 4-BENZYLOXYANILINE METHYL 4-METHYLAMINOBENZOATE 1-BENZYLOXY-4-NITROBENZENE 4-NITROPHENYL BENZOATE 1-phenylguanidine PHENYL 4-AMINOBENZOATE N-P-TOLYL-GUANIDINE NPGB METHYL 4-AMINOBENZOATE HYDROCHLORIDE N-P-TOLYL-GUANIDINE HYDROCHLORIDE P-PHENETIDINE HYDROCHLORIDE 4-(PHENOXYMETHYL)ANILINE 4-nitrophenyl 4'-guanidinobenzoate