ChemicalBook
Chinese english Germany Korea

n-ブチルアミン

n-ブチルアミン 化学構造式
109-73-9
CAS番号.
109-73-9
化学名:
n-ブチルアミン
别名:
n-ブチルアミン;ブチルアミン;1-アミノブタン;ノルバラミン;ブタン-1-アミン;1-ブタンアミン;1-ブタナミン;1-アミノブタン(n-ブチルアミン);N‐ブチルアミン;1-ブチルアミン;1 - アミノブタン(n- ブチルアミン);n - ブチルアミン;1-ブチルアミン, 99%
英語化学名:
Butylamine
英語别名:
BA;MNBA;AMINE C4;n-C4H9NH2;Butylamin;FEMA 3130;BUTYLAMINE;Butanamine;Norvalamine;Norralamine
CBNumber:
CB6361286
化学式:
C4H11N
分子量:
73.14
MOL File:
109-73-9.mol

n-ブチルアミン 物理性質

融点 :
−49 °C(lit.)
沸点 :
78 °C(lit.)
比重(密度) :
0.74 g/mL at 25 °C(lit.)
蒸気密度:
2.5 (vs air)
蒸気圧:
68 mm Hg ( 20 °C)
屈折率 :
n20/D 1.401(lit.)
FEMA :
3130 | BUTYLAMINE
闪点 :
30 °F
貯蔵温度 :
2-8°C
溶解性:
water: miscible
酸解離定数(Pka):
10.77(at 20℃)
外見 :
Liquid
色:
Clear
PH:
12.6 (100g/l, H2O, 20℃)
臭い (Odor):
Fish-like; ammonia-like.
爆発限界(explosive limit):
1.5-9.8%(V)
水溶解度 :
MISCIBLE
Sensitive :
Air Sensitive
Merck :
14,1543
JECFA Number:
1582
BRN :
605269
暴露限界値:
Ceiling 5 ppm (~15 mg/m3) (ACGIH, MSHA, and OSHA); IDLH 2000 ppm (NIOSH).
安定性::
Stable. Incompatible with oxidizing agents, aluminium, copper, copper alloys, acids. Highly flammable.
CAS データベース:
109-73-9(CAS DataBase Reference)
NISTの化学物質情報:
1-Butanamine(109-73-9)
EPAの化学物質情報:
1-Butanamine(109-73-9)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  F,C
Rフレーズ  11-20/21/22-35
Sフレーズ  3-16-26-29-36/37/39-45
RIDADR  UN 1125 3/PG 2
WGK Germany  1
RTECS 番号 EO2975000
34
自然発火温度 594 °F
TSCA  Yes
国連危険物分類  3
容器等級  II
HSコード  29211980
有毒物質データの 109-73-9(Hazardous Substances Data)
毒性 LD50 orally in rats: 500 mg/kg (Hine)
消防法 危-4-1-II
化審法 (2)-132
安衛法 57,57-2
絵表示(GHS)
注意喚起語 Danger
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H225 引火性の高い液体および蒸気 引火性液体 2 危険 P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H290 金属腐食のおそれ 金属腐食性物質 1 警告 P234, P390, P404
H302 飲み込むと有害 急性毒性、経口 4 警告 P264, P270, P301+P312, P330, P501
H311 皮膚に接触すると有毒 急性毒性、経皮 3 危険 P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 重篤な皮膚の薬傷?眼の損傷 皮膚腐食性/刺激性 1A, B, C 危険 P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H330 吸入すると生命に危険 急性毒性、吸入 1, 2 危険 P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H370 臓器の障害 特定標的臓器有害性、単回暴露 1 危険 P260, P264, P270, P307+P311, P321,P405, P501
H372 長期にわたる、または反復暴露により臓器の障 害 特定標的臓器有害性、単回暴露 1 危険 P260, P264, P270, P314, P501
H402 水生生物に有害 水生環境有害性、急性毒性 3
注意書き
P210 熱/火花/裸火/高温のもののような着火源から遠ざ けること。-禁煙。
P233 容器を密閉しておくこと。
P240 容器を接地すること/アースをとること。
P260 粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P264 取扱い後は皮膚をよく洗うこと。
P264 取扱い後は手や顔をよく洗うこと。
P270 この製品を使用する時に、飲食または喫煙をしないこ と。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P303+P361+P353 皮膚(または髪)に付着した場合:直ちに汚染された衣 類をすべて脱ぐこと/取り除くこと。皮膚を流水/シャワー で洗うこと。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
P310 ただちに医師に連絡すること。
P370+P378 火災の場合:消火に...を使用すること。

n-ブチルアミン 価格 もっと(25)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01AFAL03575 1-ブチルアミン, 99%
1-Butylamine, 99%
109-73-9 500mL ¥4600 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01AFAL03575 1-ブチルアミン, 99%
1-Butylamine, 99%
109-73-9 100mL ¥3480 2018-12-26 購入
東京化成工業 B0707 ブチルアミン >99.0%(GC)(T)
Butylamine >99.0%(GC)(T)
109-73-9 25mL ¥1700 2018-12-04 購入
東京化成工業 B0707 ブチルアミン >99.0%(GC)(T)
Butylamine >99.0%(GC)(T)
109-73-9 500mL ¥3000 2018-12-04 購入
関東化学株式会社(KANTO) 04357-00 n‐ブチルアミン >98.0%(GC)
n‐Butylamine >98.0%(GC)
109-73-9 500mL ¥3000 2018-12-13 購入

n-ブチルアミン MSDS


1-Butanamine

n-ブチルアミン 化学特性,用途語,生産方法

外観

無色~ほとんど無色, 澄明の液体

溶解性

水, アルコール, エーテルと混和。水、エタノール及びアセトンに極めて溶けやすい。

用途

界面活性剤?有機ゴム薬品?染料?医薬?農薬?原料、食品添加物、触媒

説明

n-Butylamine is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine, and isobutylamine. It is a colourless to yellow liquid and is highly flammable. It is stable and incompatible with oxidising agents, aluminium, copper, copper alloys, and acids. n-Butylamine finds its uses in the manufacture of pesticides (such as thiocarbazides), pharmaceuticals, and emulsifiers. It is also a precursor for the manufacture of N,N′-dibutylthiourea, a rubber vulcanisation accelerator, and n-butylbenzenesulphonamide, a plasticiser of nylon.

化学的特性

n-Butylamine is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine, and isobutylamine. It is a highly flammable, colorless to yellow liquid. It is stable and/but incompatible with oxidizing agents, aluminium, copper, copper alloys, and acids. n-Butylamine is used in the manufacture of pesticides (such as thiocarbazides), pharmaceuticals, and emulsifi ers. It is also a precursor for the manufacture of N,N’-dibutylthiourea, a rubber vulcanization accelerator, and n-butylbenzenesulfonamide, a plasticizer of nylon.

化学的特性

Butyl amines are highly flammable, colorless liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:

化学的特性

colourless to yellow liquid

化学的特性

n-Butylamine is a derivative of ammonia in which one of the hydrogen atoms is replaced with an alkyl group of four carbons. As such, it reacts with water and acids to form bases and salts, respectively. Acting as a very weak acid, it can react with acyl halides, anhydrides, and esters. With carbon disulfide and carbon dioxide, it forms the butyl ammonium salt of dithiocarbamic and carbamic acids, respectively. With isocyanic acid and alkyl or aryl isocyanates, it forms substituted ureas. When reacted with nitrous acid, rc-butylamine forms butyl alcohol with the release of nitrogen (Schweizer et al 1978).
In the presence of water, rc-butylamine may corrode some metals (General Electric Co 1986) and attack glass (Schweizer et al 1978). Liquid n-butylamine also will attack some forms of plastics, rubber, and coatings (NIOSH 1981).

化学的特性

Butylamine has an ammoniacal odor (fishy, pungent).

天然物の起源

Reported found in mulberry leaves, kale, tomato, tilsit cheese, cheddar and other cheeses, caviar, fish, cooked chicken, cooked beef, beer, sherry and red wine.

使用

n-Butylamine is used as an intermediatefor various products, including dyestuffs,pharmaceuticals, rubber chemical, synthetictanning agents, and emulsifying agents. It isused for making isocyanates for coatings.

使用

Intermediate for pharmaceuticals, dyestuffs, rubber chemicals, emulsifying agents, insecticides, synthetic tanning agents.

定義

ChEBI: A primary aliphatic amine that is butane substituted by an amino group at position 1.

製造方法

Catalytic alkylation of ammonia with butyl alcohol.

調製方法

n-Butylamine is usually manufactured by the catalytic alkylation of ammonia with butyl alcohol, or similarly from butyraldehyde and ammonia in the presence of Raney nickel. U.S. production in 1982 was approximately 1109 metric tons (SRI 1985). Some n-butylamine is also produced as a result of fertilizer manufacture, fish processing, rendering plant operations, and sewage treatment and has been reported to be a component of animal waste (Graedel 1978).

Aroma threshold values

Detection: 50 ppm

一般的な説明

A clear colorless liquid with an ammonia-like odor. Flash point 10°F. Less dense (6.2 lb / gal) than water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion.

空気と水の反応

Highly flammable. Dissolves in water with evolution of heat. The resulting solutions are basic.

反応プロフィール

N-BUTYL AMINE reacts violently with strong oxidizing agents and acids. Attacks copper and copper compounds [Handling Chemicals Safely 1980 p. 123]. Reacts with hypochlorites to give N-chloroamines which may be explosive when isolated [Bretherick 1979 p. 108].

危険性

Skin irritant. Flammable, dangerous fire risk. Eye and upper respiratory tract irritant.

健康ハザード

n-Butylamine is a severe irritant to the eyes,skin, and respiratory tract. Contact of theliquid with the skin and eyes can producesevere burns. Irritation effect on rabbits’ eyeswas as severe as that produced by ethylamine(ACGIH 1986). Exposure can cause irritationof the nose and throat, and at high concen trations, pulmonary edema. Scherberger andassociates (1960) have reported erythema ofthe face and neck occurring within 3 hoursafter exposure to n-butylamine, along with aburning and itching sensation.
n-Butylamine is more toxic than is eithern-propylamine or ethylamine. A 4-hourexposure to 3000-ppm concentration in airwas lethal to rats. Toxic symptoms in animalsfrom ingestion include increased pulse rate,labored breathing, and convulsions. Cyanosisand coma can occur at near-lethal dose.
LD50 value, oral (rats): 366 mg/kg
LD50 value, skin (guinea pigs): 366 mg/kg.

健康ハザード

Workers exposed on a daily basis to 5 to 10 p.p.m n-butylamine complain of nose, throat, and eye irritation and headaches. Daily exposures of less than 5 p.p.m. produce no complaints or symptoms while concentrations between 10 and 25 p.p.m. become intolerable (Beard and Noe 1981). Exposure to excessive concentrations of vapor may result in erythema, faintness, coughing, chest pains, dizziness, depression, convulsions, narcosis, and unconsciousness. Contact with the eyes may cause burns, severe damage and loss of vision. Ingestion of n-butylamine causes irritation to the mouth, throat, and gastro-intestinal tract and may cause nausea, vomiting, and shock (General Electric Co 1986). NIOSH recommends that employees working with n-butylamine should be screened for history of chronic respiratory, skin, or eye disease which might place them at increased risk from exposure (HSDB 1988).

健康ハザード

Inhalation causes irritation, nausea, vomiting, headache, faintness, severe coughing and chest pains; can cause lung edema. Ingestion causes severe irritation of mouth and stomach. Contact with eyes causes severe irritation and edema of the cornea. Contact with skin causes burns; absorption through skin may cause nausea, vomiting and shock.

健康ハザード

Exposures to butylamine (inhalation, ingestion, and through skin contact) are harmful. It is very destructive to the mucous membranes and causes, redness, severe deep burns, and loss of vision. Symptoms include, but are not limited to, sore throat, cough, burning sensation, headache, fl ushing of the face, vomiting, dizziness, abdominal pain, diarrhea, nausea, shock or collapse, shortness of breath, labored breathing, depression, convulsions, narcosis, and possibly unconsciousness. Exposure of this nature is unlikely, however, because of the irritating properties of the vapor. On catching fi re, butylamine gives off irritating or toxic fumes (or gases). Repeated or prolonged contact with the skin may cause dermatitis. The vapor is corrosive to the eyes, skin, and respiratory tract, and causes lung edema.

火災危険

Flash Point (°F): 30 ℃, 10 ℃; Flammable Limits in Air (%): 1.7-9.8; Fire Extinguishing Agents: Alcohol foam, dry chemical, carbon dioxide; Fire Extinguishing Agents Not To Be Used: Water may be ineffective; Special Hazards of Combustion Products: Toxic oxides of nitrogen may form during fires; Behavior in Fire: Vapor is heavier than air and can travel distances to ignition source and flash back. Containers may explode; Ignition Temperature (°F): 594; Electrical Hazard: No data; Burning Rate: 5.8 mm/min.

化学反応性

Reactivity with Water No reaction; Reactivity with Common Materials: May corrode some metals in presence of water; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Flush with water; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

工業用途

n-Butylamine is an important intermediate in the production of pharmaceuticals, dyestuffs, synthetic tanning agents, insecticides, emulsifying agents, rubber accelerators, vulcanizing agents, and antioxidants (HSDB 1988). A flavor ingredient in seafood and chocolate, n-butylamine is also reported to be used in alcoholic beverages, ice cream, candy, baked goods, gelatins, and puddings all at a concentration of 0.1 p.p.m. (Fenaroli 1975). It is estimated that 50% of the n-butylamine produced is used for rubber processing chemicals and 50% as an intermediate in pesticide production (SRI 1982).

安全性プロファイル

Poison by ingestion, skin contact, and intravenous routes. Moderately toxic by inhalation, intraperitoneal, and parenteral routes. A corrosive and severe skin irritant. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. A flammable liquid and dangerous fire hazard when exposed to heat, flame, or oxidzing materials. To fight fire, use alcohol foam, Con, dry chemical. Explodes on contact with perchloryl fluoride. When heated to decomposition it emits toxic fumes of NO,. See also AMINES.

職業ばく露

Alert: (n-isomer): Possible risk of forming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergic reaction), (sec-isomer): Drug. n-Butylamine is used in pharmaceuticals; dyestuffs, rubber, chemicals, emulsifying agents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as a fungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate (a lube oil additive); as an intermediate in the production of rubber and in rust preventatives and emulsion deterrents in petroleum products. It is used in the manufacture of several drugs

応急処置

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Rinse out mouth and do not induce vomiting. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy

代謝

Considering the industrial importance of this amine, it is surprising that no thorough studies of its metabolism have been completed. Aliphatic amines, in general, are well-absorbed from the gut and respiratory tract and readily metabolised (Beard and Noe 1981; Magos and Manson 1983). After oral administration of n-butylamine hydrochloride to humans, little n-butylamine was recovered in the urine (Rechenberger 1940) suggesting that extensive metabolism occurs. Deamination of n-butylamine has been shown to occur in slices of rat liver and brain cortex (Pugh and Quastel 1937). It is assumed that monoamine oxidase plays a role in the detoxication process by catalyzing the deamination of n-butylamine to ammonia, hydrogen peroxide, and butyraldehyde. The ammonia produced is then converted to urea and the hydrogen peroxide is reduced by catalase. The aldehyde is probably converted to the corresponding carboxylic acid by aldehyde oxidase (Beard and Noe, 1981).

貯蔵

n-Butylamine should be protected against physical damage. Store in a cool, dry, wellventilated location, away from any area where the fi re hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfer to avoid static sparks.

輸送方法

UN1125 n-Butylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material. UN2014 Isobutylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material

純化方法

Dry it with solid KOH, K2CO3, LiAlH4, CaH2 or MgSO4, then reflux it with, and fractionally distil it from P2O5, CaH2, CaO or BaO. Further purification is by precipitation as the hydrochloride, m 213-213.5o, from ethereal solution by bubbling HCl gas into it. This is re-precipitated three times from EtOH by adding ether, followed by liberation of the free amine using excess strong base. The amine is extracted into ether, which is separated, dried with solid KOH, the ether removed by evaporation and then the amine is distilled. It is stored in a desiccator over solid NaOH [Bunnett & Davis J Am Chem Soc 82 665 1960, Lycan et al. Org Synth Coll Vol II 319 1943]. [Beilstein 4 IV 540.] SKIN IRRITANT.

不和合性

May form explosive mixture with air. May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reacts with strong oxidizers and acids, causing fire and explosion hazard. Incompatible with organic anhydrides; isocyanates, vinyl acetate; acrylates, substituted allyls; alkylene oxides; epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in presence of moisture. The tert-isomer will attack some forms of plastics

廃棄物の処理

Use a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed.

n-ブチルアミン 上流と下流の製品情報

原材料

準備製品


n-ブチルアミン 生産企業

Global( 245)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21930 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1750 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20516 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23982 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20094 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4660 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 sale@aladdin-e.com China 24991 65

109-73-9(n-ブチルアミン)キーワード:


  • 109-73-9
  • Butylamin
  • Butylamine, n
  • femanumber3130.
  • Monobutilamina
  • Monobutylamine
  • n-Butilamina
  • N-Butylamin
  • n-C4H9NH2
  • Norralamine
  • Norvalamine
  • n-Butylamine, 99.50%
  • n-Butylamine, 99.8%
  • n-BUTYLAMINE extrapure AR
  • n-BUTYLAMINE pure
  • tert.-Butylamin
  • BUTYLAMINE
  • FEMA 3130
  • BA
  • n-Butylamine, 99+%
  • 1-Aminobutane, n-Butylamine
  • N-Butylamine, 99.5%
  • n-bytylamine
  • n-Butylamine, synthesis grade
  • n-Butylamine, reagent grade
  • n-ButylaMine, 99.5% 1LT
  • ButylaMine(BTA)
  • BUTYLAMINE FOR SYNTHESIS 2,5 L
  • BUTYLAMINE FOR SYNTHESIS 1 L
  • BUTYLAMINE, 99.5%, 99.5%
  • 1-Butylamine 0
  • n-ブチルアミン
  • ブチルアミン
  • 1-アミノブタン
  • ノルバラミン
  • ブタン-1-アミン
  • 1-ブタンアミン
  • 1-ブタナミン
  • 1-アミノブタン(n-ブチルアミン)
  • N‐ブチルアミン
  • 1-ブチルアミン
  • 1 - アミノブタン(n- ブチルアミン)
  • n - ブチルアミン
  • 1-ブチルアミン, 99%
  • アルキルアミン
  • 構造分類
  • 官能性 & α,ω-二官能性アルカン
  • 一官能性アルカン
Copyright 2017 © ChemicalBook. All rights reserved