グラブリジン

グラブリジン 価格 もっと(10)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01CHDASB-00007234	グラブリジン Glabridin	59870-68-7	5mg	￥91800	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01CHDASB-00007234	グラブリジン Glabridin	59870-68-7	10mg	￥145800	2024-03-01	購入
関東化学株式会社(KANTO)	49063-80	グラブリジン Glabridin	59870-68-7	10mg	￥88000	2024-03-01	購入
Sigma-Aldrich Japan	G9548	グラブリジン ≥98% (HPLC), powder Glabridin ≥98% (HPLC), powder	59870-68-7	5mg	￥20900	2024-03-01	購入
Sigma-Aldrich Japan	53633	グラブリジン analytical standard Glabridin analytical standard	59870-68-7	10mg	￥155000	2023-06-01	購入

グラブリジン 化学特性,用途語,生産方法

外観

白色～うすい黄褐色, 結晶～粉末

定義

本品は、次の化学式で表される有機化合物である。

溶解性

エタノールに溶け、水にほとんど溶けない。

化粧品の成分用途

皮膚ブリーチ剤

化学的特性

White to tan powder, insoluble in water, easily soluble in organic solvents such as ethanol, propylene glycol, 1,3-butanediol, etc.

使用

Glabridin is a compound extracted from Licorice (root) shows properties that are cytotoxic, antimicrobial, estrogenic and anti-proliferative.

定義

ChEBI: Glabridin is a member of the class of hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2' and 4' and a 2,2-dimethyl-2H-pyran group across positions 7 and 8 respectively. It has a role as an antiplasmodial drug. It derives from a hydride of a (R)-isoflavan.

利点

Glabridin has strong antibacterial effects and can prevent inflammation, pigmentation, and rough skin caused by ultraviolet rays. It can also remove superoxide ions and inhibit hemolysis caused by hydrogen peroxide. Moreover, it can inhibit the activity of tyrosinase and the conversion of dopachrome, making it an effective and environmentally-friendly additive for whitening and freckle removal in cosmetics. Additionally, Glabridin possesses similar abilities to scavenge oxygen free radicals as SOD (superoxide dismutase) and vitamin E, making it a powerful antioxidant.

Mode of action

Glabridin[59870-68-7] is one of the main flavonoid components in Glycyrrhiza glabra. It shows a strong anti-free radical oxidation effect in the cytochrome P450/NADPH oxidation system, which can significantly inhibit the free radicals produced in the metabolic process of the body, to avoid oxidative damage to oxidation-sensitive biological macromolecules (low-density lipoprotein LDL, DNA) and the cell wall, etc. by free radical oxidation. Thus, it can prevent certain pathological changes related to free radical oxidation, such as atherosclerosis, and cellular aging. In addition, Glabridin has some hypolipidemic and hypotensive effects.

参考文献

Glabridin, a functional compound of liquorice, attenuates colonic inflammation in mice with dextran sulphate sodium‐induced colitis DOI:10.1111/j.1365-2249.2007.03539.x
Structural insights into the binding behavior of isoflavonoid glabridin with human serum albumin DOI:10.1016/J.FOODHYD.2019.01.031
A novel ?uorescent recombinant cell-based biosensor for screening NLRP3 inflammasome inhibitors DOI:10.1016/j.snb.2019.126864
Glavonoid, a possible supplement for prevention of ATTR amyloidosis DOI:10.1016/j.heliyon.2021.e08101
Tian, M. et al.: Int. J. Mol. Sci., 9, 571 (2008); Simmler, C. et al.: Fitoterapia, 90, 160 (2013);

グラブリジン 上流と下流の製品情報

原材料

準備製品

グラブリジン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	dominicguo@gk-bio.com	CHINA	9427	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+8618829768577	gao490372054@gamil.com	China	1250	58
Hebei Kingfiner Technology Development Co.Ltd	+86-15532196582 +86-15373005021	lisa@yibangte.com	China	2987	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Wuhan Quanjinci New Material Co.,Ltd.	+8615271838296	kyra@quanjinci.com	China	1532	58
BINBO BIOLOGICAL CO.,LTD	+8618629063126	info@binbobiological.com	China	290	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Sinopharm International Guangzhou Ltd.	+86-2038033341 +86-18520036739	zhuluqiang@sinopharm.com	China	77	58
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58

59870-68-7(グラブリジン)キーワード:

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• 59870-68-7
• 1,3-Benzenediol, 4-(3,4-dihydro-8,8-diMethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-, (R)-
• (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol
• 4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl]-1,3-benzenediol
• Glabridin, >=98%
• Glabridin/Propylene Glycol
• 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
• GLABRIDIN
• 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[6,5-f]chromen-3-yl]benzene-1,3-diol
• 4-((R)-8,8-Dimethyl-3,4-dihydro-2H,8H-benzo[1,2-B:4,3-B']dipyran-3-yl)-benzene-1,3-diol
• Aids096010
• Aids-096010
• GLABRIDIN(RG)
• GLABRIDIN (GLYCYRRHIZA GLABRA ROOT EXTRACT)
• 4-(8,8-DiMethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chroMen-3-yl)-benzene-1,3-diol
• 2H,8H-Benzo[1,2-b:3,4-b']dipyran,1,3-benzenediolderiv
• Liquorice flavonoids
• Glabridin, froM Liquorice root
• Glabridin/OIL SOLUBLE LICORICE(GLYCYRRHIZA) EXTRACT
• professional manufacturer Glabridin 59870-68-7
• 98% Glabridin 59870-68-7 Light-yellow powder
• Light liquorice set
• LGB-GD 90
• LGB-GD 40
• Soluble GLABRIDIN, Liposomal GLABRIDIN, GLABRIDIN NanoEmulsion, NanoActive GLABRIDIN
• BioaActive Glabridin
• Nanoactive Glabridin
• Soluble Glabridin
• 1,3-Benzenediol,4-[(3R)-3,4-dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-
• Glabridin, 98%, from Liquorice root
• KB-289522
• グラブリジン
• 4-(8,8-ジメチル-3,4-ジヒドロ-2H,8H-ベンゾ[1,2-b:3,4-b′]ジピラン-3β-イル)-1,3-ベンゼンジオール
• 4-[(3R)-8,8-ジメチル-2H,3H,4H,8H-ピラノ[2,3-f]クロメン-3-イル]ベンゼン-1,3-ジオール
• 4-[[(R)-3,4-ジヒドロ-8,8-ジメチル-2H,8H-ベンゾ[1,2-b:3,4-b′]ジピラン]-3-イル]-1,3-ベンゼンジオール
• 4-[[(R)-3,4-ジヒドロ-8,8-ジメチル-2H,8H-ベンゾ[1,2-b:3,4-b′]ジピラン]-3β-イル]-1,3-ベンゼンジオール
• 生物学・臨床用標準物質
• 一般医薬品