eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem

 化学構造式
304475-63-6
CAS番号.
304475-63-6
化学名:
别名:
英語名:
eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem
英語别名:
eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem;InSolution eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem;2-Propenamide, 3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-
CBNumber:
CB84813855
化学式:
C21H17Cl3N4OS
分子量:
479.81
MOL File:
304475-63-6.mol

eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem 物理性質

比重(密度) :
1.474±0.06 g/cm3(Predicted)
酸解離定数(Pka):
10.70±0.70(Predicted)

安全性情報

eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem 化学特性,用途語,生産方法

一般的な説明

A cell-permeable and selective inhibitor of the phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Shown to offer protection against ER stress-induced apoptosis (EC50 ~15 μM in PC12 cells stimulated with 750 ng/ml of Tunicamycin (Cat. No. 654380). Prevents HSV replication both in Vero cells (IC50 ~3 μM for reducing plaque formation) in vitro and in a mouse cornea infection model in vivo. The solid form of this compound (Cat. No. 324895) is also available.

Biochem/physiol Actions

Cell permeable: yes

eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem 上流と下流の製品情報

原材料

準備製品


eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem 生産企業

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  • 304475-63-6
  • eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem
  • InSolution eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem
  • 2-Propenamide, 3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-
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