りん酸1,2-ジブロモ-2,2-ジクロロエチルジメチル 化学特性,用途語,生産方法
外観
ごくうすい黄色～うすい黄色, 澄明の液体
溶解性
水に不溶。脂肪族炭化水素以外の殆どの有機溶媒に可溶。水にほとんど溶けない。芳香族溶媒に容易に溶ける。アセトンに溶け、水にほとんど溶けない。
用途
農薬(接触性?食毒性の殺虫?殺ダニ剤)
使用上の注意
アルゴン封入
説明
Sensitization to Naled seems to be rare.
化学的特性
Naled is a white crystalline solid (when pure)
or light straw-colored liquid (above 26.7℃) with a slightly
pungent insecticide odor.
物理的性質
Colorless to pale yellow liquid or solid with a pungent odor
使用
Naled is used to control mites, sucking pests and some other
insects in a wide variety of crops. It is also used for the control of public
and animal health pests including mosquitoes.
定義
ChEBI: An dialkyl phosphate resulting from the formal condensation of the acidic hydroxy group of dimethyl hydrogen phosphate with the alcoholic hydroxy group of 1,2-dibromo-2,2-dichloroethanol. An organophosphate insecticide, it is no longer approved for use wit
in the European Union.
一般的な説明
DIBROM is a white solid that may be dissolved in a liquid organic carrier with a pungent odor. DIBROM is a water emulsifiable liquid. DIBROM is insoluble in water and sinks in water. DIBROM can cause illness by inhalation, skin absorption and/or ingestion. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. If DIBROM is in liquid form, DIBROM can easily penetrate the soil and contaminate groundwater and nearby streams. DIBROM is used as a pesticide.
空気と水の反応
Practically insoluble in water [Farm Chemicals Handbook]. Hydrolyzed slowly in presence of water.
反応プロフィール
DIBROM is incompatible with the following: Strong oxidizers, acids, sunlight, water [Note: Corrosive to metals. Hydrolyzed in presence of water.] . Unstable in presence of Iron [USCG, 1999]. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
危険性
Technical compound is a moderately volatile liquid. Bp 110C (0.5 mm Hg). Insoluble in water;
slightly soluble in aliphatic solvents; very soluble
in aromatic solvents; hydrolyzes in water.
健康ハザード
INHALATION OR INGESTION: Symptoms secondary to cholinesterase inhibition are: headache, giddiness, nervousness, blurred vision, weakness, nausea, cramps, diarrhea, chest discomfort, sweating, miosis, tearing, salivation, and other excessive respiratory tract secretion, vomiting, cyanosis, muscle twitching, and convulsions. EYES: Irritating. SKIN: Irritating-can cause dermatitis.
火災危険
May be combustible. (NOAA, 2007)
农业用途
Insecticide, Fungicide, Bactericide, Acaricide: Naled is a fast-acting, nonsystemic contact and stomach
insecticide used to control aphids, mites, mosquitoes,and flies on crops and in greenhouses, mushroom houses,
animal and poultry houses, kennels, food-processing
plants, and aquaria and in outdoor mosquito control. Liquid
formulations can be applied to greenhouse heating pipes to
kill insects by vapor action. It has been used by veterinarians
to kill parasitic worms (other than tapeworms) in dogs.
Naled may no longer be used in and around the home by
residents or professional applicators. Naled is available in
dust, emulsion concentrate, liquid, and ULV formulations.
Also used in cooling towers, veterinary medicine, pulp and
paper mill systems, hospitals, swimming pools, and bathrooms.
A U.S. EPA restricted Use Pesticide (RUP). Not
approved for use in EU countries. Registered for use in
the U.S.
製品名
AI3-24988®; ARTHODIBROM®;
BROMCHLOPHOS®; BROMEX®; DIBROM®;
FLYKILLER®; LUCANAL®; HIBROM®; ORTHO®
4355; ORTHODIBROM®; ORTHODIBROMO®;
PROKIL® Naled; TRUMPET®
接触アレルゲン
Naled is an organophosphate cholinesterase inhibitor
that is used as an insecticide and acaricide. Sensitization
seems to be very rare.
職業ばく露
A potential danger to those involved
in the manufacture, formulation, and application of this
insecticide, fungicide, bactericide, acaricide. Also used in
cooling towers, veterinary medicine, pulp and paper mill
systems; hospitals, swimming pools; and bathrooms.
発がん性
When dogs were given 0.2, 2.0,
or 20 mg/kg/day naled by gavage for 1 year, cholinergic signs
(soft stools/diarrhea, salivation, and emesis), increases in
mineralization of spinal cord, and mild testicular degeneration
in males occurred at 2 and 20 mg/kg/day dose
levels . Erythrocyte and brain cholinesterase activities
were depressed at the same dose levels. Anemia also
occurred at 2 and 20 mg/kg/day, and erythrocyte count,
hemoglobin, and hematocrit were reduced. At 20 mg/kg/
day dose level, liver and kidney weights increased but
these were not accompanied by histopathological changes.
There was no evidence of carcinogenicity.
環境運命予測
Chemical/Physical. Completely hydrolyzed in water within 2 days (Windholz et al.,
1983). In the presence of metals or reducing agents, naled loses bromine, forming dichlorvos
(Hartley and Kidd, 1987)
Naled emits toxic fumes of bromines, chlorides and phosphorus oxides when heated
to decomposition (Lewis, 1990).
代謝経路
Naled is produced by the photochemical bromination of the dichlorovinyl
moiety of dichlorvos. The main route of naled metabolism and transformation
in the environment is through debromination to dichlorvos
which is probably the active cholinesterase inhibitor in vivo. Naled is also
rapidly hydrolysed to bromodichloroacetaldehyde in aqueous environments:
consequently much of its detoxification is likely to be via a nonenzymatic
hydrolytic route.
輸送方法
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. UN2783 Organophosphorus pesticides,
solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
UN3018 Organophosphorus pesticides, liquid, toxic,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
不和合性
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Hydrolyzed in presence of
water. Degraded by sunlight. Decomposes when heated; on
contact with acids, acid fumes; bases, producing fumes of
hydrogen chloride, hydrogen bromide, phosphorous oxides.
Reacts with acids, strong oxidizers in sunlight. Slowly
reacts with water; hydrolysis is; corrosive to metals.
Attacks some plastics, rubber and coatings.
廃棄物の処理
This pesticide is more
stable to hydrolysis than dichlorvos (50% hydrolysis at pH
9 @ 37.5℃ in 301 minutes). It is unstable in alkaline conditions,
in presence of iron; and is degraded by sunlight.
About 10% hydrolysis per day is obtained in ambient
water. Incineration is recommended for large amounts.
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must
be disposed properly by following package label directions
or by contacting your local or federal environmental control
agency, or by contacting your regional EPA office.
りん酸1,2-ジブロモ-2,2-ジクロロエチルジメチル 上流と下流の製品情報
原材料
準備製品