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무고소나무잎오일

무고소나무잎오일
무고소나무잎오일 구조식 이미지
카스 번호:
8000-26-8
한글명:
무고소나무잎오일
동의어(한글):
무고소나무잎오일
상품명:
PINE NEEDLES OIL DWARF
동의어(영문):
Pine Oil;kneepineoil;DwarfPineOil;pine leaf oil;PineNeedlesOil;kiefernadeloel;Pine Needle Oil;PINUSOILPUMILIO;Oils,pineneedle;pinusmontanaoil
CBNumber:
CB0189930
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

무고소나무잎오일 속성

안전

독성 LD50 oral in rat: 6880mg/kg
기존화학 물질 KE-27213

무고소나무잎오일 C화학적 특성, 용도, 생산

화학적 성질

Dwarf-pine-needle oil is obtained in Austria (Tyrol) and other mountainous areas of Central and Southeast Europe by steam distillation of fresh needles and twig tips of Pinus mugo Turra ssp. mugo and ssp. pumilio (Haenke) Franco. It is a colorless liquid with a pleasant, balsamic odor.
d2020 0.858–0.868; n20D 1.474–1.478; α20D ?15 ° to ?7 °; solubility: 1 vol in ≤10 vol of 90% ethanol. Content by GC: α-pinene 10–30%;β-pinene 3–14%; 3-carene 5–25%; β-phellandrene 8–17%; limonene 8–14%; bornyl acetate 1–5%.

화학적 성질

The essential oil is obtained by steam or steam-water distillation of the comminuted needles and twigs in yields of 0.3 to 0.4%. The oil has a pleasant aromatic odor and bitter, pungent taste.

물리적 성질

It is a clear, almost colorless, mobile liquid.

출처

Found in the branches and adherent leaves of P. mugo Turra var. pumilio (Fam. Pinaceae) (Guenther, 1952).

제조 방법

By steam distillation of the branches and leaves of P. mugo Turra var. pumilio (Guenther, 1952).

Essential oil composition

Main constituents include l-α-pinene, β-pinene, l-limonene, dipentene, l-phellandrene, aldehydes, various esters, and alcohols.

Pharmacology

In man. Pinus pumilio oil increased bronchial secretions (Thomas, 1958). A dose of 500 mg/kg was reported to have no effect in vivo on the metabolism and pharmacological activity of pentobarbitone (25 mg/kg) in rats or in vitro on the metabolism of amidopyrene, p-nitroanisole and aniline by rat liver (Jori et al. 1969). Intravenous injection of the oil dissolved in sorbitol monostearate water caused no toxic effects in warm-blooded animals and large doses caused no changes in blood pressure, but it showed digitalis-like action of the isolated toad heart (Primavori. 1960).

Safety Profile

Mildly toxic by ingestion. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

신진 대사

Following immersion of young pigs and one human subject for 30 min in baths containing 150 ml of a pine-oil mixture (Fichtennadel-Latschenkiefer?l. Kneipp) in 450 litres of water, a- and ?-pinene and limonene (components of Latschenkiefer?l) were detected in the exhaled air within 20 min, reaching maximum levels 50-75 min after the start of the bath and remaining detectable after 1 day (R?mmelt, Zuber. Dirnagl. & Drexel. 1974).

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