1,1,3,3-테트라메틸부틸이소시아나이드
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1,1,3,3-테트라메틸부틸이소시아나이드 속성
- 끓는 점
- 55-57 °C11 mm Hg(lit.)
- 밀도
- 0.794 g/mL at 25 °C(lit.)
- 굴절률
- n
20/D 1.422(lit.)
- 인화점
- 125 °F
- 저장 조건
- 2-8°C
- 용해도
- insol water; sol common organic solvents
- 물리적 상태
- 투명한 액체
- 색상
- 무색 내지 거의 무색
- BRN
- 2076559
- CAS 데이터베이스
- 14542-93-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 10-20/21/22 | ||
| 안전지침서 | 23-36/37 | ||
| 유엔번호(UN No.) | UN 1993 3/PG 3 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 10-21 | ||
| HS 번호 | 2929 90 00 | ||
| 위험 등급 | 3.2 | ||
| 포장분류 | III |
1,1,3,3-테트라메틸부틸이소시아나이드 C화학적 특성, 용도, 생산
화학적 성질
clear colorless liquid용도
1,1,3,3-Tetramethylbutyl isocyanide was used in the synthesis of substituted furans and imides.제조 방법
To a stirred solution of 83.0 g (0.528 mole) of N-(l,l,3,3-tetramethylbutyl) formamide in 11 of DMF was added dropwise, under a nitrogen atmosphere, a solution made up of thionyl chloride (40.3 ml, 0.55 mole) dissolved in 150 ml of DMF. The addition was at such a rate that the temperature did not exceed -50°C. After the addition, the cooling bath was removed momentarily to allow the temperature to increase to -35°C and then it was replaced while 118.0 g (1.11 mole) of sodium carbonate (anhydrous grade) was added. Then the cooling bath was removed and the reaction mixture was diluted with ice-cold water in a separatory funnel and then extracted with pentane. The pentane extract was dried over sodium sulfate and concentrated, and the product distilled to yield 68.4 g (93% yield), b.p. 55.5-56.6°C (11 mm). Infrared spectrum (neat) 2110 c m " 1 (s); nmr (neat) 51.08 [s, 9, C(CH3) 2] , 1.43 [t, 6, J = 2Hz, C(CH3) 2] , 1.58 (t, 2, J = 2.3 Hz, CH2).
주요 응용
1,1,3,3-Tetramethylbutyl isocyanide can be added to organometallic reagents to obtain α-metal aldehyde imines, which are used to synthesize useful acyl anion equivalents.Synthesis
1,1,3,3-Tetramethylbutyl isocyanide is readily available in two steps from 1,1,3,3-tetramethylbutylamine, which is formylated with Formic Acid (86- 90%) followed by dehydration with Dimethylchloromethyleneammonium Chloride (Vilsmeier reagent).1,1,3,3-테트라메틸부틸이소시아나이드 준비 용품 및 원자재
원자재
준비 용품
1,1,3,3-테트라메틸부틸이소시아나이드 공급 업체
글로벌( 106)공급 업체
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