NBI 35965 hydrochloride
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NBI 35965 hydrochloride 속성
- 녹는점
- 167 °C
- 저장 조건
- Store at -20°C
- 용해도
- Soluble in DMSO > 10 mM
- 물리적 상태
- 가루
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
NBI 35965 hydrochloride C화학적 특성, 용도, 생산
용도
Corticotropin-releasing hormone, also known as corticotropin-releasing factor (CRF) or corticoliberin, is a peptide hormone and neurotransmitter involved in the stress response. It is secreted from the hypothalamus and is the major regulator of pituitary corticotropin-release and consequent glucocorticoid secretion. NBI 35965 is a selective CRF receptor 1 (CRF1) antagonist with a Ki value of 4 nM. It does not inhibit CRF2 (Ki = >10,000 nM). NBI 35965 inhibits cAMP accumulation and adrenocorticotropic hormone (ACTH) production in vitro (pIC50s = 7.1 and 6.9, respectively) and reduces CRF- and stress-induced ACTH production in vivo. In animal models of stress, NBI 35965 administration produces anxiolytic effects.[Cayman Chemical]NBI 35965 hydrochloride 준비 용품 및 원자재
원자재
준비 용품
NBI 35965 hydrochloride 공급 업체
글로벌( 23)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 |
757984502@qq.com | China | 892 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131981 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 |
sales@pharmacodia.com | China | 2317 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 |
2853530910@QQ.com | China | 8011 | 62 |
| Lynnchem | 86-(0)29-85992781 17792393971 |
info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 |
info@novachemistry.com | United Kingdom | 4381 | 58 |
| BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |