5-PAHSA
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5-PAHSA 속성
- 저장 조건
- -20°C
- 용해도
- DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 그림문자(GHS): |
 
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| 신호 어: | Danger | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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5-PAHSA C화학적 특성, 용도, 생산
용도
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. 5-PAHSA is a FAHFA in which palmitic acid is esterified at the 5th carbon of hydroxy stearic acid. PAHSA isoforms are the most abundant forms of FAHFA identified in the adipose tissue of glucose tolerant AG4OX mice. PAHSAs are synthesized in vivo in both mice and humans and are regulated by fasting and high-fat feeding in mice. PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. PAHSA administration lowers ambient glycemia, improves glucose tolerance, and stimulates GLP-1 and insulin secretion in mice.[Cayman Chemical]일반 설명
Palmitic acid and hydroxystearic acid (PAHSA) containing (O-acyl)-hydroxy fatty acids are being found in tissues and serum extracts of mouse and human.Biochem/physiol Actions
Palmitic acid and hydroxystearic acid (PAHSA) levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through G-protein-coupled receptor 120 (GPR120) to enhance insulin-stimulated glucose uptake. PAHSAs are fatty acid esters of hydroxy fatty acids (FAHFAs), which are endogenous lipids with the potential to treat diabetes and inflammation.5-PAHSA 준비 용품 및 원자재
원자재
준비 용품
5-PAHSA 공급 업체
글로벌( 24)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 |
info@creative-enzymes.com | United States | 8748 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44894 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 |
gaojun@univ-bio.com | China | 24998 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 8740 | 58 |