1-Bromo-2-butyne
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1-Bromo-2-butyne 속성
- 끓는 점
- 40-41 °C/20 mmHg (lit.)
- 밀도
- 1.519 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.508(lit.)
- 인화점
- 97 °F
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 아세토니트릴과 혼합 가능.
- 물리적 상태
- 액체
- Specific Gravity
- 1.519
- 색상
- 투명하고 연한 황록색
- BRN
- 605306
- InChI
- InChI=1S/C4H5Br/c1-2-3-4-5/h4H2,1H3
- InChIKey
- LNNXOEHOXSYWLD-UHFFFAOYSA-N
- SMILES
- C(Br)C#CC
- CAS 데이터베이스
- 3355-28-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험 카페고리 넘버 | 10 | ||
|---|---|---|---|
| 안전지침서 | 16-24/25 | ||
| 유엔번호(UN No.) | UN 1993 3/PG 3 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 10-23 | ||
| 위험 등급 | 3 | ||
| 포장분류 | III | ||
| HS 번호 | 29033990 | ||
| 스토리지 클래스 | 3 - Flammable liquids | ||
| Hazard Classifications | Flam. Liq. 3 |
1-Bromo-2-butyne C화학적 특성, 용도, 생산
화학적 성질
Clear pale yellow-greenish liquid용도
1-Bromo-2-butyne is used in the preparation of six to eight annulated ring compounds in reaction with indoles and pseudopterane (+/-)-Kallolide B, which is a marine natural product. Further, it acts as a precursor in the preparation of axially chiral teranyl compounds, alkylation of L-tryptophan methyl ester, 4-butynyloxybenzene sulfonyl chloride and mono-propargylated diene derivative. In addition to this, it is also used in the synthesis of isopropylbut-2-ynylamine, allenylcyclobutanol derivatives, allyl-[4-(but-2-ynyloxy)phenyl]sulfane, allenylindium and axially chiral teranyl compounds.제조 방법
1-bromo-2-butyne is obtained by reacting 2-butyn-1-ol and organic solvent, pyridine.First react bromoethane with metal magnesium in THF to prepare Grignard reagent, then add paraformaldehyde to Grignard reagent for Grignard reaction, separate and recover after Grignard reaction 2-butyn-1-ol, then mix 2-butyn-1-ol with organic solvent and pyridine, add phosphorus tribromide dropwise for bromination reaction, separate and recover the product after bromination reaction.일반 설명
1-Bromo-2-butyne is a propargyl bromide derivative. It is one of the constitutional isomer of bromo butyne. Its Br-loss threshold photoionization breakdown diagram has been analyzed to derive dissociative photoionization thresholds to C4H5+ production. It participates in the preparation of linagliptin.1-Bromo-2-butyne 준비 용품 및 원자재
원자재
준비 용품
1-Bromo-2-butyne 공급 업체
글로벌( 440)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Emeishan Hongsen Biopharmaceutical Co., Ltd. | 0833-6186278 19162541913 |
sales@hongshengpharm.com | China | 99 | 60 |
| Chengdu Maidisen Biotechnology Co., Ltd. | 19981944287 |
info@cdmds.com | China | 111 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 |
market03@meryer.com | China | 40202 | 62 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51389 | 80 |
| Anqing CHICO Pharmaceutical Co., Ltd. | 18061456370 |
sales@chicopharm.com | China | 500 | 65 |
| Nantong Subei Chemical Raw Materials Co., Ltd. | 0513-85290972 18762756250 |
ntsbhg@163.com | China | 9277 | 58 |
| Jiangsu Haici Biopharmaceutical Co., Ltd. | 15722465851 15722465851 |
2545001360@qq.com | China | 183 | 58 |
| Shanghai Newthink Biotechnology Co., Ltd. | 18121861491 |
3847526528@qq.com | China | 107 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 |
saleschina@alfa-asia.com | China | 30103 | 84 |
1-Bromo-2-butyne 관련 검색:
4-브로모-1-부틴 2-부틴 1,4-디브로모-2-부틴 1-(3-BROMO-1-PROPYNYL)나프탈렌 1-브로모-2-옥틴
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