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1-BROMO-2-BUTYNE

1-BROMO-2-BUTYNE Structure
1-BROMO-2-BUTYNE structure
CAS No.
3355-28-0
Chemical Name:
1-BROMO-2-BUTYNE
Synonyms
1-Bromobut-2-yne;2-BUTYNYL BROMIDE;1-Bromobut-2-butyne;1-Brom-2-Butin;1-BROMO-2-BUTYNE;Linagliptin INT4;1-broMo -2-Ding Que;1-Bromo-2-butyne,98%;1-BROMO-2-BUTYNE 98%;1-Bromo-2-butyne >
CBNumber:
CB0363349
Molecular Formula:
C4H5Br
Molecular Weight:
132.99
MDL Number:
MFCD00190233
MOL File:
3355-28-0.mol
MSDS File:
SDS
Last updated:2023-12-26 17:07:23
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1-BROMO-2-BUTYNE Properties

Boiling point 40-41 °C/20 mmHg (lit.)
Density 1.519 g/mL at 25 °C (lit.)
refractive index n20/D 1.508(lit.)
Flash point 97 °F
storage temp. Inert atmosphere,Room Temperature
solubility Miscible with acetonitrile.
form Liquid
Specific Gravity 1.519
color Clear pale yellow-greenish
BRN 605306
InChIKey LNNXOEHOXSYWLD-UHFFFAOYSA-N
CAS DataBase Reference 3355-28-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H226
Precautionary statements  P261-P303+P361+P353-P305+P351+P338-P405-P501a-P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501
Risk Statements  10
Safety Statements  16-24/25
RIDADR  UN 1993 3/PG 3
WGK Germany  3
F  10-23
HazardClass  3
PackingGroup  III
HS Code  29033990
NFPA 704
3
2 0

1-BROMO-2-BUTYNE price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 427292 1-Bromo-2-butyne 99% 3355-28-0 1g $31.2 2024-03-01 Buy
Sigma-Aldrich 427292 1-Bromo-2-butyne 99% 3355-28-0 5g $145 2024-03-01 Buy
TCI Chemical B2190 1-Bromo-2-butyne >96.0%(GC) 3355-28-0 1g $38 2024-03-01 Buy
TCI Chemical B2190 1-Bromo-2-butyne >96.0%(GC) 3355-28-0 5g $104 2024-03-01 Buy
Alfa Aesar L20134 1-Bromo-2-butyne, 98% 3355-28-0 5g $130 2024-03-01 Buy
Product number Packaging Price Buy
427292 1g $31.2 Buy
427292 5g $145 Buy
B2190 1g $38 Buy
B2190 5g $104 Buy
L20134 5g $130 Buy

1-BROMO-2-BUTYNE Chemical Properties,Uses,Production

Chemical Properties

Clear pale yellow-greenish liquid

Uses

1-Bromo-2-butyne is used in the preparation of six to eight annulated ring compounds in reaction with indoles and pseudopterane (+/-)-Kallolide B, which is a marine natural product. Further, it acts as a precursor in the preparation of axially chiral teranyl compounds, alkylation of L-tryptophan methyl ester, 4-butynyloxybenzene sulfonyl chloride and mono-propargylated diene derivative. In addition to this, it is also used in the synthesis of isopropylbut-2-ynylamine, allenylcyclobutanol derivatives, allyl-[4-(but-2-ynyloxy)phenyl]sulfane, allenylindium and axially chiral teranyl compounds.

Preparation

1-bromo-2-butyne is obtained by reacting 2-butyn-1-ol and organic solvent, pyridine.First react bromoethane with metal magnesium in THF to prepare Grignard reagent, then add paraformaldehyde to Grignard reagent for Grignard reaction, separate and recover after Grignard reaction 2-butyn-1-ol, then mix 2-butyn-1-ol with organic solvent and pyridine, add phosphorus tribromide dropwise for bromination reaction, separate and recover the product after bromination reaction.

General Description

1-Bromo-2-butyne is a propargyl bromide derivative. It is one of the constitutional isomer of bromo butyne. Its Br-loss threshold photoionization breakdown diagram has been analyzed to derive dissociative photoionization thresholds to C4H5+ production. It participates in the preparation of linagliptin.

1-BROMO-2-BUTYNE synthesis

764-01-2
7789-60-8
3355-28-0
Synthesis of 1-BROMO-2-BUTYNE from 2-Butyn-1-ol and Phosphorus tribromide

1-BROMO-2-BUTYNE Preparation Products And Raw materials

Raw materials

Preparation Products

1-PHTHALIMIDO-2-BUTYNE 2-Butyn-1-amine, N-2-propyn-1-yl- DI-BUT-2-YNYL-AMINE 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione

1-BROMO-2-BUTYNE Suppliers

Global( 404)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Rochi Pharmaceutical Co.,Ltd.
21-38751876 +8615000076078 info@rochipharma.com China 431 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Hebei Dangtong Import and export Co LTD 		+8615632927689 admin@hbdangtong.com China 991 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838 chloewu@chicopharm.cn CHINA 341 58
Supplier Advantage
Shanghai Rochi Pharmaceutical Co.,Ltd.
58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Dangtong Import and export Co LTD 		58
Henan Fengda Chemical Co., Ltd 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Anqing Chico Pharmaceutical Co., Ltd. 		58

View Lastest Price from 1-BROMO-2-BUTYNE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-BROMO-2-BUTYNE pictures 2024-04-26 1-BROMO-2-BUTYNE
3355-28-0
 US $30.00-20.00 / kg 1kg 99% 20Tons Hebei Dangtong Import and export Co LTD
1-bromo-2-butyne pictures 2024-03-28 1-bromo-2-butyne
3355-28-0
 US $0.00 / kg 25kg 98%-99% Inquiry PNP Biotech Co. Ltd
1-BROMO-2-BUTYNE pictures 2023-12-26 1-BROMO-2-BUTYNE
3355-28-0
 US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • 1-BROMO-2-BUTYNE pictures
  • 1-BROMO-2-BUTYNE
    3355-28-0
  • US $30.00-20.00 / kg
  • 99%
  • Hebei Dangtong Import and export Co LTD

1-BROMO-2-BUTYNE Spectrum

1-BROMO-2-BUTYNE(3355-28-0)MS1-BROMO-2-BUTYNE(3355-28-0)IR1

3355-28-0(1-BROMO-2-BUTYNE)Related Search:

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1-BROMO-2-BUTYNE 1-BROMO-2-BUTYNE 98% 1-Bromo-2-butyne,98% But-2-yn-1-yl bromide 1-broMo -2-Ding Que 1-BroMo-2-butyne, 96.0%(GC) Linagliptin INT4 1-Bromo-2-butyne (Linagliptin) 1-BROMO-2-BUTYNE, 2-BUTYNYL BROMIDE 1-Brom-2-Butin Linagliptin intermediates，1-bromo-2-butyne 1-BROMO-2-BUTYNE ISO 9001：2015 REACH 1-Bromo-2-butyne > 1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98% 1-Bromobut-2-yne 95% 2-BUTYNYL BROMIDE 1-Bromobut-2-yne 1-Bromobut-2-butyne Rilpivirine Impurity 18 3355-28-0 2563355-28-0 CH3CCCH2Br Br1C4H5 CH3C8801CCH2Br C4H5Br Organic Building Blocks Halogenated Hydrocarbons Acetylenes Functionalized Acetylenes Alkynyl Building Blocks Intermediates Acetylenes Functionalized Acetylenes Alkynyl Halogenated Hydrocarbons Organic Building Blocks