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디메티콘

디메티콘
디메티콘 구조식 이미지
카스 번호:
9006-65-9
한글명:
디메티콘
동의어(한글):
디메티콘;디메티콘(DIMETHICONE);디메티콘코폴리올
상품명:
Dimethicone
동의어(영문):
KM 9;HL 88;KHS 7;E 1049;Hedrin;HL 999;D01540;DC 1428;DC 1664;CFS-F(M)
CBNumber:
CB0696472
분자식:
C6H18OSi2
포뮬러 무게:
162.37752
MOL 파일:
9006-65-9.mol

디메티콘 속성

밀도
1 g/mL at 20 °C
증기압
5 mm Hg ( 20 °C)
굴절률
n20/D 1.406
인화점
121 °C
용해도
Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, miscible with ethyl acetate, with methyl ethyl ketone and with toluene.
물리적 상태
neat
안정성
Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, organics, acids, alkalis. Corrodes many metals.
InChIKey
UQEAIHBTYFGYIE-UHFFFAOYSA-N
CAS 데이터베이스
9006-65-9
EPA
Dimethicone (9006-65-9)

안전

위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 24/25-26
WGK 독일 3
RTECS 번호 TQ2690000
유해 물질 데이터 9006-65-9(Hazardous Substances Data)

디메티콘 MSDS


Dimethicone

디메티콘 C화학적 특성, 용도, 생산

화학적 성질

colourless to slightly yellow liquid

화학적 성질

Dimethicones are clear, colorless liquids available in various viscosities.

용도

A silicone oil consisting of a mixture of fully methylated linear siloxane polymers end-blocking with trimethylsiloxy units. Commonly used in skin and hair products.

용도

dimethicone is a form of silicone used to give products lubricity, slip, and good feel. It can also serve as a formulation defoamer and help reduce the feeling of greasiness that some creams leave on the skin immediately upon application. In addition, dimethicone is reported to protect the skin against moisture loss when used in larger quantities. It improves product flow and spreadability. In combination with other ingredients, dimethicone becomes a good waterproofing material for sunscreen emulsions, and helps reduce the greasiness often seen in high-SPF preparations.

Indications

Silicone (dimethicone) ointments are excellent water-protective agents because they have an extremely low surface tension and penetrate crevices in the skin to form a plastic-like barrier. Further, they are nontoxic, inert, stable, and water repellent. As such, they are useful as barrier creams in industry or wherever constant or frequent exposure to aqueous compounds is a problem. They will not, however, protect well against solvents, oils, or dusts.

정의

ChEBI: A polydimethylsiloxane macromolecule, composed of dimethylsiloxane repeating units.

생산 방법

Dimethicone isapoly (dimethylsiloxane) obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. The hydrolysis products contain active silanol groups through which condensation polymerization proceeds. By varying the proportions of chlorotrimethylsilane, which acts as a chain terminator, silicones of varying molecular weight may be prepared. Different grades of dimethicone are produced that may be distinguished by a number placed after the name indicating the nominal viscosity. For example, ABIL 20 (Evonik Goldschmidt UK Ltd) has a nominal kinematic viscosity of 18–22mm2/s (18–22cSt).

상표명

Sentry Dimethicone (Witco); Sentry Dimethicone Dispension (Witco).

Pharmaceutical Applications

Dimethicones of various viscosities are widely used in cosmetic and pharmaceutical formulations. In topical oil-in-water emulsions dimethicone is added to the oil phase as an antifoaming agent. Dimethicone is hydrophobic and is also widely used in topical barrier preparations. Therapeutically, dimethicone may be used with simethicone in oral pharmaceutical formulations used in the treatment of flatulence. Dimethicone is also used to form a waterrepellent film on glass containers.

Safety

Dimethicone is generally regarded as a relatively nontoxic and nonirritant material although it can cause temporary irritation to the eyes. In pharmaceutical formulations it may be used in oral and topical preparations. Dimethicones are also used extensively in cosmetic formulations and in certain food applications.
The WHO has set a tentative estimated acceptable daily intake of dimethicone with a relative molecular mass in the range of 200–300 at up to 1.5mg/kg body-weight. 
Injection of silicones into tissues may cause granulomatous reactions. Accidental intravascular injection has been associated with fatalities.

저장

Dimethicones should be stored in an airtight container in a cool, dry, place; they are stable to heat and are resistant to most chemical substances although they are affected by strong acids. Thin films of dimethicone may be sterilized by dry heat for at least 2 hours at 160°C. Sterilization of large quantities of dimethicone by steam autoclaving is notrecommended since excesswater diffuses intothe fluid causing it to become hazy. However, thin films may be sterilized by this method. Gamma irradiation may also be used to sterilize dimethicone. Gamma irradiation can, however, cause crosslinking with a consequent increase in the viscosity of fluids.

Regulatory Status

Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules and tablets, topical creams,emulsions,lotions,and transdermal preparations).Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

디메티콘 준비 용품 및 원자재

원자재

준비 용품


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