METHYLERGONOVINE

METHYLERGONOVINE 구조식 이미지
카스 번호:
113-42-8
상품명:
METHYLERGONOVINE
동의어(영문):
Partergin;Prestwick_727;Methylergometrin;Methylergobrevin;Methylergobasine;METHYLERGONOVINE;methylergometrine;Methylergonovine-D3;METHYLERGONOVINE USP/EP/BP;Methylergonovine (Methylergometrine)
CBNumber:
CB0833158
분자식:
C20H25N3O2
포뮬러 무게:
339.44
MOL 파일:
113-42-8.mol

METHYLERGONOVINE 속성

녹는점
172-173℃ (decomposition)
알파
D20 -45° (c = 0.4 in pyridine)
끓는 점
475.4°C (rough estimate)
밀도
1.1492 (rough estimate)
굴절률
1.6650 (estimate)
저장 조건
Desiccate at RT
산도 계수 (pKa)
pKa 6.65± 0.03(H2O,t =24,I<0.01)(Approximate)
색상
MeOH/Me2CO로부터 프리즘형 결정의 침전

안전

유해 물질 데이터 113-42-8(Hazardous Substances Data)
독성 LD50 orl-rat: 93 mg/kg 27ZIAQ -,163,73

METHYLERGONOVINE C화학적 특성, 용도, 생산

화학적 성질

Shiny crystals; melts at 172°C (341.6°F);moderately soluble in water, dissolves readilyin alcohol and acetone.

용도

Methylergonovine is a drug currently used as a smooth muscle constrictor during postpartum hemorrhage, as an inhibitor of the inflammasome complex in ASC-mediated procaspase-1 activation screening.

건강위험

The toxic effects due to methylergonovine inhumans include nausea, vomiting, dizziness,and hypertension. The oral and intravenousLD50 values in mice are 187 and 85 mg/kg,respectively.

생물학적 활성

Active metabolite of methysergide ; uterotonic agent and oxytocic.

Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.

METHYLERGONOVINE 준비 용품 및 원자재

원자재

준비 용품


METHYLERGONOVINE 공급 업체

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