GLY-ARG-GLY-ASP-SER-PRO-LYS

GLY-ARG-GLY-ASP-SER-PRO-LYS 구조식 이미지
카스 번호:
111119-28-9
상품명:
GLY-ARG-GLY-ASP-SER-PRO-LYS
동의어(영문):
GRGDSPK;EMD 56574;GRGDSPK (EMD 56574);GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC);glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
CBNumber:
CB1123649
분자식:
C28H49N11O11
포뮬러 무게:
715.76
MOL 파일:
111119-28-9.mol
MSDS 파일:
SDS

GLY-ARG-GLY-ASP-SER-PRO-LYS 속성

밀도
1.59±0.1 g/cm3(Predicted)
저장 조건
-20°C
산도 계수 (pKa)
3.60±0.21(Predicted)

안전

WGK 독일 3

GLY-ARG-GLY-ASP-SER-PRO-LYS C화학적 특성, 용도, 생산

용도

Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-
  • as a blocking peptide to inhibit integrin-fibronectin binding
  • in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
  • for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
  • for the preparation of RGD.Flt23k.NR nanoparticles
  • to determine the involvement of RGD-integrin bonding in cell adhesion process

일반 설명

Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.

Biochem/physiol Actions

Fibronectin analog that binds to integrins.

GLY-ARG-GLY-ASP-SER-PRO-LYS 준비 용품 및 원자재

원자재

준비 용품


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