SR3335

SR3335 구조식 이미지
카스 번호:
293753-05-6
상품명:
SR3335
동의어(영문):
ML-176;SR3335;SR3335;ML176;ML-176;SR-3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR 3335 (This product is only available in Japan.);N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide;N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide;2-Thiophenesulfonamide, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-
CBNumber:
CB12628427
분자식:
C13H9F6NO3S2
포뮬러 무게:
405.3358792
MOL 파일:
293753-05-6.mol
MSDS 파일:
SDS

SR3335 속성

저장 조건
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도
insoluble in H2O; ≥87.4 mg/mL in EtOH; ≥88.8 mg/mL in DMSO
물리적 상태
고체
물리적 상태
단단한 모양

안전

SR3335 C화학적 특성, 용도, 생산

개요

The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It is without effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis.

SR3335 준비 용품 및 원자재

원자재

준비 용품


SR3335 공급 업체

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