1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
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1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 속성
- 녹는점
- 86-88
- 끓는 점
- 281.4±36.0 °C(Predicted)
- 밀도
- 1.070±0.06 g/cm3(Predicted)
- 증기압
- 0.049Pa at 20℃
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 클로로포름과 디클로로메탄에 용해됩니다.
- 물리적 상태
- powder to crystal
- 산도 계수 (pKa)
- 6.19±0.70(Predicted)
- 색상
- 밝은 노란색에서 갈색까지
- InChIKey
- MZLRFUCMBQWLNV-FNORWQNLSA-N
- LogP
- 0.26 at 20℃ and pH7.2
- 표면장력
- 71.8mN/m at 1.008g/L and 20℃
- CAS 데이터베이스
- 55314-16-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38 | ||
안전지침서 | 26-36/37/39 | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29333990 |
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one C화학적 특성, 용도, 생산
개요
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one can be used in the synthesis of imatinib and nilotinib (AMN107), a compound currently in multiple Phase II/III clinical trials for chronic granulocytic leukaemia. Imatinib, on the other hand, is a cancer growth blocker known as a tyrosine kinase inhibitor (TKI), which is used to treat a wide range of leukaemias, myelodysplastic/myeloproliferative disorders, systemic mastocytosis, eosinophilia syndromes, raised dermal fibrosarcoma and gastrointestinal mesenchymal tumours.화학적 성질
Off-White SolidSolubility in organics
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one is soluble in Chloroform and Dichloromethane.1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 준비 용품 및 원자재
원자재
준비 용품
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 공급 업체
글로벌( 256)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Yangzhou Qinyuan Pharmatech Co.,ltd | +86-18752526868 |
jennysun@yzqyyykj.com | China | 71 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 811 | 58 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9355 | 55 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 |
chloewu@chicopharm.cn | CHINA | 341 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2966 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5909 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14335 | 58 |
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 관련 검색:
3-(디메틸아미노)프로필아민 P-다이메틸아미노벤즈알데하이드 4-다이메틸아미노피리딘 2-아미노피리딘 3-아미노피리딘 4-다이메틸아미노벤조산 2-디메틸아미노에탄올
N-Desmethyl Imatinib
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
1-[2-[BIS(TERT-BUTYL)PHOSPHINO]PHENYL]-3,5-DIPHENYL-1H-PYRAZOLE
1-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-Ethanone
1-(4,6-dibromothieno[3,4-b]thiophen-2-yl)-2-ethylhexan-1-one
1-(4,6-dibroMo-3-fluorothieno[3,4-b]thiophen-2-yl)-2ethylhexan-1-one
1-(2,3-Dichlorophenyl)piperazine hydrochloride
Imatinib Meta-methyl-piperazine Impurity
Imatinib Impurity 7
N-DESMETHYL IMATINIB
4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide