졸레드로네이트이나트륨사수화물
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졸레드로네이트이나트륨사수화물 속성
- 녹는점
- 305-307°C
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 메탄올(약간 용해됨, 가열, 초음파 처리), 물(약간 용해됨, 가열)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
안전
졸레드로네이트이나트륨사수화물 C화학적 특성, 용도, 생산
개요
Zoledronate was introduced in Canada as a lyophilized powder in vials for infusion as solution in the treatment of tumor-induced hypercalcemia. This third-generation bisphosphonate can be obtained by reaction of 2-(1-imidazolyl)acetic acid hydrochloride with phosphorous trichloride followed by hydrolysis in concentrated hydrochloric acid, Zoledronate originated from a medicinal chemistry program started at Novartis, Switzerland in 1986 and aimed at discovering a follow-up to pamidronate for the treatment of osteoporosis and metastatic bone disease. It has highly potent inhibitory effect on hypercalcemia induced by vitamin Ds both in vitro in mouse calvarial cultures and in viva in the thyroparathyroidectomized rat. It is respectively 100 and 850-fold more potent than pamidronate in the former and latter tests. Clinically, it was demonstrated that zoledronate achieved normalized serum calcium concentrations in a significantly higher percentage of cancer patients compared to pamidronate. The 5 minute infusion with zoledronate was more convenient than the 2 hour infusion necessary with pamidronate.화학적 성질
White Crystalline Powder용도
A biphosphonate bone resorption inhibitor.졸레드로네이트이나트륨사수화물 준비 용품 및 원자재
원자재
준비 용품
졸레드로네이트이나트륨사수화물 공급 업체
글로벌( 39)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15394 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
AN PharmaTech Co Ltd | 86(21)68097365 |
sales@anpharma.net | China | 4901 | 55 |
Aikon International Limited | 025-66113011 13155353615 |
qzhang@aikonchem.com | China | 15396 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 |
sales@rrkchem.com | China | 56086 | 58 |
졸레드로네이트이나트륨사수화물 관련 검색:
인산 나트륨, 이염기 에틸렌디아민테트라아세트산, 이나트륨 염 이미다졸 나트륨 (1-히드록시에틸리덴)비스포스폰 산 1-히드록시에틸리덴-1,1-디포스포닌산
Sodium Monofluorophosphate
Zofenoprilat
Zoledronic acid hydrate
[15N2,13C2]-Zoledronic Acid
Zoledronic Acid Trihydrate
Zoledronic-d3 Acid
Zoledronic acid
Pamidronate disodium salt
CHLOROPHOSPHONAZO III
8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT
Etidronic acid monohydrate
Β-GLYCEROPHOSPHATE, DISODIUM SALT
Zoledronate disodium tetrahydrate