눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P332+P313
피부 자극이 생기면 의학적인 조치· 조언을 구하시오.
P337+P313
눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
1- 브로 모 -9H- 카바 졸 C화학적 특성, 용도, 생산
화학적 성질
White to yellow powder or crystals.
용도
1-Bromo-9H-carbazole is a useful research chemical, mainly used as a pharmaceutical intermediate and an intermediate in organic synthesis.
제조 방법
A 1-Bromo-9H-carbazole is synthesized as follows：Under noble gas protection, by 3,6- bis- Tert-butyl carbazole is dissolved in 1,2- dichloroethanes, adds hydrobromic acid, controlling reaction temperature to be slowly added dropwise hydrogen peroxide, dropping is completely Overnight, reactant liquor is washed, and separates organic layer for natural temperature reaction, is dried, and adds methyl alcohol dispersion, obtains the tertiary fourth of bromo- 3, the 6- of 1- bis- Base carbazole；Then 1- bromo- 3,6- di-t-butyl carbazole and isopropanol solvent are added in reaction bulb, controlling reaction temperature slowly adds Enter alchlor reaction, add water after terminating terminating reaction, through extraction, organic layer sodium hydrate aqueous solution is washed, and is dried overnight, concentrate Obtain crude product, methylene chloride-methanol mixed solvent is recrystallized to give product 1-Bromo-9H-carbazole. Production method of 1-bromocarbazole
정의
1-Bromo-9H-carbazole is a bromide-substitution of carbazole. The carbazole ring system is essentially planar (r.m.s. deviation of 0.024? for the non-H atoms). It is a photoelectric material intermediate and be used to synthesize OLED materials.
