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킨세노사이드

킨세노사이드 구조식 이미지

카스 번호:: 151870-74-5

한글명:: 킨세노사이드

동의어(한글):: 킨세노사이드

상품명:: Kinsenoside

동의어(영문):: Kinsenoside;(+)-Kinsenoside;(4R)-4-(beta-D-Glucopyranosyloxy)dihydro-2(3H)-furanone;2(3H)-Furanone, 4-(β-D-glucopyranosyloxy)dihydro-, (4R)-;(4R)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-one;(R)-4-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)dihydrofuran-2(3H)-one;Keap1-Nrf2,Inhibitor,pulposus,disc,degeneration,Kinsenoside,inhibit,cells,nucleus,Nrf2,Apoptosis,intervertebral

CBNumber:: CB22645474

분자식:: C10H16O8

포뮬러 무게:: 264.23

MOL 파일:: 151870-74-5.mol

속성

안전

용도

공급 업체 109

킨세노사이드 속성

끓는 점: 570.2±50.0 °C(Predicted)

밀도: 1.59±0.1 g/cm3(Predicted)

저장 조건: 4°C, protect from light

용해도: DMF:14.0(Max Conc. mg/mL);52.98(Max Conc. mM)
DMSO:33.0(Max Conc. mg/mL);124.89(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);37.85(Max Conc. mM)

물리적 상태: 결정성 고체

산도 계수 (pKa): 12.81±0.70(Predicted)

색상: White to light yellow

안전

킨세노사이드 C화학적 특성, 용도, 생산

개요

Kinsenoside is a glycoside originally isolated from A. formosanus that has diverse biological activities, including antihyperlipidemic, immunosuppressive, and anti-inflammatory properties. It increases lipolysis mediated by adipose triglyceride lipase and increases hydrolysis of triglycerides in C3H10T1/2 adipocytes. It also increases phosphorylation of peroxisome proliferator-activated receptor α (PPARα) and CREB as well as protein levels of SIRT1, PGC-1α, and carnitine palmitoyltransferase I. Kinsenoside downregulates the expression and phosphorylation of VEGF receptor 2 (VEGFR2) and inhibits crosstalk between the JAK2/STAT3 and PI3K/AKT signaling pathways in dendritic cells in vitro. It decreases the production of IFN-γ, IL-17, and TNF-α and increases the production of IL-10 in splenocytes isolated from mice with collagen-induced arthritis (CIA). Kinsenoside (300 mg/kg per day) decreases the expression of IL-1β, TNF-α, and matrix metalloproteinase-9 (MMP-9) and increases the expression of IL-10 in inflamed joints in a mouse model of collagen-induced arthritis and prevents paw edema and reduces the severity of arthritis.

용도

Kinsenoside is an anti-hyperlipidemic agent isolated from the plant Anoect chilus.

킨세노사이드 준비 용품 및 원자재

원자재

준비 용품

킨세노사이드 공급 업체

글로벌( 109)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30250	58
Aktin Chemicals, Inc.	028-85159085	info@aktinchem.com	CHINA	1025	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58

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