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Verbascoside

Verbascoside 구조식 이미지
카스 번호:
61276-17-3
상품명:
Verbascoside
동의어(영문):
ACTEOSIDE;ISOVERBASCOSIDE;Acetoside;Kusagi;TJC 160;KUSAGININ;NSC 603831;Russetinol;Verbacoside;VERBASCOSIDE
CBNumber:
CB2306760
분자식:
C29H36O15
포뮬러 무게:
624.59
MOL 파일:
61276-17-3.mol

Verbascoside 속성

녹는점
232℃
끓는 점
908.8±65.0 °C(Predicted)
밀도
1.60±0.1 g/cm3(Predicted)
저장 조건
Sealed in dry,Room Temperature
용해도
DMSO (Slightly), Ethyl Acetate (Very Slightly), Methanol (Slightly)
산도 계수 (pKa)
9.31±0.10(Predicted)
물리적 상태
Solid
색상
White to Pale Yellow
안정성
Hygroscopic
InChIKey
FBSKJMQYURKNSU-ZLSOWSIRSA-N
CAS 데이터베이스
61276-17-3(CAS DataBase Reference)

안전

안전지침서 24/25
WGK 독일 2
RTECS 번호 LZ5786000
HS 번호 29389090
독성 LD50 oral in rat: > 5gm/kg

Verbascoside C화학적 특성, 용도, 생산

화학적 성질

White solid

용도

Verbascoside is an agent producing effects on anti-GBM nephritis in rats. Effective agent against glomerulonephritis. Phenolic anti-oxidant agent.

효소 저해제

This plant glycoside and antioxidant (FW = 624.60 g/mol; CAS 61276-173), also known as verbascoside, inhibits TNFa-mediated apoptosis in LPSstimulated macrophages as well as 1-methyl-4-phenylpyridiniuminduced apoptosis in cerebellar granule neurons. It also inhibits proliferation of human promyelocytic HL-60 leukemia cells by inducing cell cycle arrest at the G0/G1 phase, followed by differentiation into monocytes. Acteoside inhibits PMA-induced invasion and migration of human fibrosarcoma cells by Ca2+-dependent CaMK/ERK and JNK/NFκB-signaling pathways. Acteoside thus shows the potential as antimetastatic agent. Another intriguing finding is that acteoside inhibits amyloid-β aggregation. Target(s): aldose reductase; protein kinase C; integrase, HIV-1; peptidyl-dipeptidase A, or angiotensin-converting enzyme; tyrosinase, or monophenol monooxygenase; 5-lipoxygenase, or arachidonate 5-lipoxygenase.

Verbascoside 준비 용품 및 원자재

원자재

준비 용품


Verbascoside 공급 업체

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