3,4-디메톡시페놀
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3,4-디메톡시페놀 속성
- 녹는점
- 79-82 °C (lit.)
- 끓는 점
- 167°C/14mm
- 밀도
- 1.1690 (rough estimate)
- 굴절률
- 1.4740 (estimate)
- 인화점
- 167°C/14mm
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 10.08±0.18(Predicted)
- 물리적 상태
- 미세 결정성 분말
- 색상
- 미색부터 밝은 베이지까지
- 수용성
- 물에 용해됩니다.
- 감도
- Light Sensitive
- BRN
- 1366650
- LogP
- 1.157 (est)
- CAS 데이터베이스
- 2033-89-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
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위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 26-36-37/39 | ||
WGK 독일 | 3 | ||
F 고인화성물질 | 10 | ||
TSCA | Yes | ||
HS 번호 | 29095000 |
3,4-디메톡시페놀 C화학적 특성, 용도, 생산
화학적 성질
Red Crystal Powder용도
3,4-Dimethoxyphenol is used in the preparation of 5,6-dimethoxy benzofuranone derivatives and multi-target anti Alzheimer compounds. It is also used in the preparation of 3,4-dimethoxyphenyl-beta-D-glucopyranoside and 4-(but-2-enyloxy)-1,2-dimethoxybenzene. Further, it serves as a precursor for 4H-chromenes synthesis.Synthesis
3,4-Dimethoxyphenol is synthesised using Veratraldehyde as a raw material by chemical reaction. The specific synthesis steps are as follows:Method (i): To a solution of vertraldehyde (2.11)(5 g,0.03 mole)in glacial acetic acid (30 ml)is added dropwise to a solution of peracetic acid5(15 ml) during 30 min.The temperature of the reaction mixture rises,it is kept at 40-45 by cooling.The reaction mixture is left for 10 hr and then concentrated to about 15 ml in vacuo.The residue is extracted with ether (2 x 20 ml).The ether layer is distilled.The formate ester of 3,4- dimethoxyphenol thus obtained is hydrolysed by refluxing with potassium hydroxide (10 g)in aqueous alcohol (1:4,100 ml)for 1 hr.The reaction mixture is concentrated in vacuo almost to dryness.It is dissolved in water (20 ml),the solution rendered acidic with dilute sulphuric acid and extracted with ether.The ether extract is dried (sodium sulphate)and distilled.The oily residue thus obtained is subjected to column chromatography over silica gel(2 x 30 cm).Elution with benzene gave 3,4-dimethoxyphenol as yellow solid.Yield 3g(65.2%).It is crystallised from benzene as yellow crystalline needles.M.p.78-80(lit.m.p.78-80).
Method (ii): A mixture of veratraldehyde (2.11)(1.66 g,0.01 mole),hydrogen peroxide (30%,2.6 ml,0.023 mole),p-toluenesulphonic acid (6.88 g, 0.036 mole)and methanol (5 ml)is stirred at room temperature.When the reaction is complete (as monitored by TLC)the reaction mixture is diluted with water (50 ml)and extracted with dichloromethane (5 x 50 ml).The extract is dried (anhydrous sodium sulphate)and purified by column chromatography over silica gel(2 x 30 cm).Elution with benzene gave 3,4. dimethoxyphenol as an yellow solid.Yield 1.16 g (75.3%).M.p.78-80.
3,4-디메톡시페놀 준비 용품 및 원자재
원자재
Phenol, 3,4-dimethoxy-, 1-formate
3,4,4-트리메톡시-2,5-사이클로헥사디엔-1-온
2',4',6'-트리하이드록시-3'-메틸부티로페논
N-(3,4-디메톡시페닐)에탄아미드
3,4-Dimethoxyphenylboronic acid
4-ALLYL-2,6-DIMETHOXYPHENOL
시린잘데하이드
3-메톡시카테콜
5-TERT-부틸피로갈롤
4-브로모버레이트롤
Acetosyringone
4-HYDROXY-3-METHOXYPHENYLACETONE
준비 용품
3,4-디메톡시페놀 공급 업체
글로벌( 290)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 |
info@spring-chem.com | China | 2068 | 57 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 |
sales@chemwish.com | CHINA | 10828 | 58 |