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20ALPHA-HYDROXYCHOLESTEROL

20ALPHA-HYDROXYCHOLESTEROL 구조식 이미지

카스 번호:: 516-72-3

상품명:: 20ALPHA-HYDROXYCHOLESTEROL

동의어(영문):: C05500;20-hydroxycholesterol;20A-HYDROXYCHOLESTEROL;20α-Hydroxy Cholesterol;Cholesterol Impurity 32;5-Cholestene-3B,20a-diol;5-cholestene-3β,20α-diol;Cholest-5-ene-3,20a-diol;Cholest-5-ene-3β,20-diol;20[S]-HYDROXYCHOLESTEROL

CBNumber:: CB2372501

분자식:: C27H46O2

포뮬러 무게:: 402.65

MOL 파일:: 516-72-3.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 61

20ALPHA-HYDROXYCHOLESTEROL 속성

녹는점: 136-137°C

끓는 점: 512.3±23.0 °C(Predicted)

밀도: 1.03±0.1 g/cm3(Predicted)

저장 조건: Inert atmosphere,2-8°C

용해도: DMSO 또는 에탄올에 용해됩니다.

산도 계수 (pKa): 15.04±0.70(Predicted)

색상: 하얀색

안정성: 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.

안전

WGK 독일	3

20ALPHA-HYDROXYCHOLESTEROL C화학적 특성, 용도, 생산

개요

20(S)-hydroxy Cholesterol is an allosteric agonist of the smoothened (Smo) receptor that activates the hedgehog (Hh) signaling pathway with an EC₅₀ value of approxiately 3 μM in a gene transcription reporter assay using NIH3T3 cells. 20(S)-hydroxy Cholesterol is necessary for normal Hh signaling. It induces Smo accumulation in primary cilia, an early event in signaling, and binds to the extracellular, cysteine-rich domain of Smo. 20(S)-hydroxy Cholesterol also stimulates osteogenic differentiation of pluripotent bone marrow stromal cells, a process mediated via Hh and Notch signaling.

화학적 성질

White Solid

용도

A metabolite of Cholesterol. Cholesterol oxidation product having cytotoxicity effects

정의

ChEBI: An oxysterol that is cholesterol substituted by a hydroxy group at position 20.

20ALPHA-HYDROXYCHOLESTEROL 준비 용품 및 원자재

원자재

메틸(4-)-1-펜틴 1-브로모-4-메틸펜테인 3-tert-Butyldimethylsilyloxy Pregnenolone 콜레스테롤 Pregnenolone

준비 용품

20ALPHA-HYDROXYCHOLESTEROL 공급 업체

글로벌( 61)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9685	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17994	56
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29797	68

20ALPHA-HYDROXYCHOLESTEROL 관련 검색:

옥타데켄 노넨(시스-4-) 2,3-DIMETHYL-2-HEXANOL 4-CYCLOHEXYLCYCLOHEXANOL 5-ETHYL-3-NONANOL 3-DECANOL 5-METHYL-5-NONANOL 2-BUTYL-1-OCTANOL (S)-(+)-4-METHYL-2-PENTANOL 6-TRIDECANOL dodec-11-enol 20ALPHA-HYDROXYCHOLESTEROL 4-METHYL-5-OCTANOL 3-DODECANOL TRANS-9-DODECEN-1-OL (S)-(+)-2-NONANOL 4-METHYL-4-PENTEN-2-OL 3-METHYL-4-OCTANOL