InSolution p38 MAP Kinase Inhibitor III - Calbiochem

InSolution p38 MAP Kinase Inhibitor III - Calbiochem 구조식 이미지
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InSolution p38 MAP Kinase Inhibitor III - Calbiochem
동의어(영문):
InSolution p38 MAP Kinase Inhibitor III - Calbiochem
CBNumber:
CB34817373
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

InSolution p38 MAP Kinase Inhibitor III - Calbiochem 속성

안전

InSolution p38 MAP Kinase Inhibitor III - Calbiochem C화학적 특성, 용도, 생산

일반 설명

A cell-permeable, potent, selective, and ATP-competitive inhibitor of p38 MAP kinase (IC50 = 380 nM for p38α). Shown to effectively suppress LPS-induced cytokine release in vitro (IC50 = 160 nM for TNF-α release and 39 nM for IL-1β release, human PBMC) and in vivo (ED50 = 1.33 mg/kg for TNF-α release in mice). Exhibits reduced inhibitory activity against cytochrome P450-2D6 compared to SB 203580 (Cat. No 559389) and is better suited for use in animal models.

Biochem/physiol Actions

Cell permeable: yes

InSolution p38 MAP Kinase Inhibitor III - Calbiochem 준비 용품 및 원자재

원자재

준비 용품


InSolution p38 MAP Kinase Inhibitor III - Calbiochem 공급 업체

글로벌( 2)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

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