2-(4-메톡시벤질-N-(2-피리딜)아미노)에틸다이메틸아민말리에이트
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2-(4-메톡시벤질-N-(2-피리딜)아미노)에틸다이메틸아민말리에이트 속성
- 녹는점
- 101-103°C
- 저장 조건
- 2-8°C
- 용해도
- 물에 매우 잘 녹고 에탄올에 잘 녹습니다(96%).
- 물리적 상태
- Solid
- 색상
- 하얀색
- 수용성
- 100mg/ml의 물에 불용성
- 최대 파장(λmax)
- 310nm(EtOH)(lit.)
- Merck
- 14,7984
- 안정성
- 안정성 가연성. 강한 산화제와 호환되지 않습니다.
- LogP
- 2.751 (est)
- CAS 데이터베이스
- 59-33-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38 | ||
안전지침서 | 26-36/37 | ||
WGK 독일 | 3 | ||
RTECS 번호 | UT1225000 | ||
TSCA | Yes | ||
HS 번호 | 2933399090 | ||
독성 | LD50 orally in mice: 338 mg/kg (Hunziker) |
2-(4-메톡시벤질-N-(2-피리딜)아미노)에틸다이메틸아민말리에이트 C화학적 특성, 용도, 생산
개요
Mepyramine is a first generation antihistamine that acts as an inverse agonist at the histamine H1 receptor. It is reported to bind with high affinity to a Gq/11 protein-coupled form of the receptor and to promote a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling of the endogenously expressed receptor, as well as to reduce G protein availability for other non-related receptors associated with this signaling pathway. Mepyramine has been shown to inhibit histamine-induced inositol phosphate production with a log EC50 value of -7.94.화학적 성질
solid용도
Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.일반 설명
White crystals or powder. Melting point 100-101°C. Bitter saline taste. An antihistaminic medicine.공기와 물의 반응
Water soluble.반응 프로필
PYRILAMINE MALEATE is an acidic salt of an amine. Usually does not react as either oxidizing agents or reducing agents but such behavior is not impossible. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.건강위험
SYMPTOMS: Symptoms of exposure to PYRILAMINE MALEATE may include drowsiness, potentiation of the sedative effect of barbituates, fatigues, vertigo, incoordination, tremor, muscle weakness, dryness of the mouth and throat, tinnitus, pupillary dilation, blurred vision, urinary retention, impotence, epigastric and intestinal pain, anorexia, nausea, vomiting, diarrhea, excitation, euphoria, insomnia, nervousness, palpitation, tachycardia, hypotension, hypersensitivity reactions, respiratory depression, coma and delirium.화재위험
Flash point data for PYRILAMINE MALEATE are not available, however PYRILAMINE MALEATE is probably combustible.생물학적 활성
Selective inverse agonist for the H 1 receptor. Inhibits histamine induced inositol phosphate (InsP) production (log EC50 = -7.94) and intracellular calcium mobilization. Sequesters G q/11 protein, reducing its availability for other receptors associated with the same signaling pathway.Safety Profile
A human poison by ingestion. An experimental poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. An antihistamine. When heated to decomposition it emits toxic fumes of NOx.2-(4-메톡시벤질-N-(2-피리딜)아미노)에틸다이메틸아민말리에이트 준비 용품 및 원자재
원자재
준비 용품
2-(4-메톡시벤질-N-(2-피리딜)아미노)에틸다이메틸아민말리에이트 공급 업체
글로벌( 197)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 7930 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15394 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52861 | 58 |
Henan Alfa Chemical Co., Ltd | +8618339805032 |
alfa4@alfachem.cn | China | 13183 | 58 |
PT CHEM GROUP LIMITED | |
peter68@ptchemgroup.com | China | 35426 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 50003 | 58 |
2-(4-메톡시벤질-N-(2-피리딜)아미노)에틸다이메틸아민말리에이트 관련 검색:
디메틸에틸렌디아민 N,N-디메틸에틸렌디아민
FORMANILIDE
4-Aminodiphenylamine
2-Benzylaminopyridine
2-(4-Methoxybenzylamino)pyridine
PYRILAMINE
2-DIETHYLAMINOPYRIDINE
Tripelennamine
(METHOXYMETHYL)DIPHENYLPHOSPHINE OXIDE
PYRILAMINE MALEATE
Ammonium hydrogen maleate
N-METHYL-N-PYRIDIN-2-YLETHANE-1,2-DIAMINE
N-2-Pyridinyl-1,2-ethanediamine
N'-(5-AMINOPENTYL)-N-(4-METHOXYBENZYL)-N'-METHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE, DIMALEATE SALT
2-(ETHYLMETHYLAMINO)PYRIDINE
N-(4-Methoxybenzyl)-N-2-pyridinyl-1,2-ethanediamine
[[(2-aminoethyl)amino]methyl]phenol