REC BETA-ECGF (HUMAN)

REC BETA-ECGF (HUMAN) C화학적 특성, 용도, 생산

용도

β-Endothelial Cell Growth Factor human has been used:

• in cell death assay
• in endothelial cell culture
• in human umbilical vascular endothelial cell (HUVEC) culture

일반 설명

The β-endothelial cell growth factor (b-ECGF) gene encodes an angiogenic factor, and is mapped to human chromosome 11q13.1. Recombinant, human b-endothelial cell growth factor (b-ECGF) is a 14 amino acid N-terminal extension of acidic fibroblast growth factor. It is expressed in Escherichia coli. The 154 amino acid recombinant protein, generated after removal of the initiation methionine, has a predicted molecular mass of about 17 kDa.

Biochem/physiol Actions

β-Endothelial cell growth factor (β-ECGF) is a potent endothelial cell mitogen and its mitogenic activity is potentiated by heparin. β-ECGF stimulates the growth of quiescent HUVEC cells in culture. β-ECGF is associated with lipid and glucose metabolism. This growth factor induces neovascularization in disease conditions. Upregulation of β-ECGF is observed in diabetic retinopathy, and polycystic ovary syndrome. It is also associated with tumor proliferation and invasion. β-ECGF increases fatty acid transport proteins expression to improve endothelial mediated lipid transpor.

REC BETA-ECGF (HUMAN) 준비 용품 및 원자재

원자재

준비 용품

REC BETA-ECGF (HUMAN) 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Duling International Trade Co. LTD	+8618032673083	sales05@hbduling.cn	China	15745	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

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