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3-Deazauridine

3-Deazauridine 구조식 이미지

카스 번호:: 23205-42-7

상품명:: 3-Deazauridine

동의어(영문):: NSC-126849;3-deazuridine;3-DEAZAURIDINE;3-DEAZAURIDINE CRYSTALLINE;3Deazauridine,3 Deazauridine;3-Deazauridine,anticancer antiviral;1-β-D-Ribofuranosyl-4-hydroxy-2-pyridone;4-Hydroxy-1-(β-D-ribofuranosyl)-2-pyridone;4-Hydroxy-1-β-D-ribofuranosyl-2(1H)pyridone;4-Hydroxy-1-(beta-D-ribofuranosyl)-2-pyridone

CBNumber:: CB4125871

분자식:: C10H13NO6

포뮬러 무게:: 243.21

MOL 파일:: 23205-42-7.mol

속성

안전

용도

공급 업체 71

3-Deazauridine 속성

녹는점: 233-235°C

끓는 점: 569.2±50.0 °C(Predicted)

밀도: 1.718±0.06 g/cm3(Predicted)

저장 조건: -20°C

용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 4.50±1.00(Predicted)

색상: 흰색에서 옅은 베이지까지

InChI: InChI=1/C10H13NO6/c12-4-6-8(15)9(16)10(17-6)11-2-1-5(13)3-7(11)14/h1-3,6,8-10,12-13,15-16H,4H2/t6-,8-,9-,10-/s3

InChIKey: CBOKZNLSFMZJJA-FNMQVXAUNA-N

SMILES: [C@@H]1([C@H](O)[C@H](O)[C@@H](CO)O1)N1C=CC(O)=CC1=O |&1:0,1,3,5,r|

LogP: -1.693 (est)

안전

RTECS 번호	UV1148000

3-Deazauridine C화학적 특성, 용도, 생산

개요

3-Deazauridine is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate synthetase, which is considered to be the primary mode of action of this nucleoside analog. This compound has been shown to possess in vitro activity against leukemia L1210 tumor cells, Ehrlich ascites tumor cells, Escherichia coli, and Streptococcus faecium. Despite a paucity of clinical attention given to this drug as a single agent, it has generated much enthusiasm as a biological response modulator because of its synergistic effect with several antitumor agents, including Cytosine Arabinoside, 5-aza-2'-deoxycytidine, 5-azacytidine, thymidine and D-galactosamine. However, only the cytosine arabinoside/3-Deazauridine combination has been explored clinically[1-2].

용도

Antimetabolite antiviral dosing regimen for hepatitis C virus or flaviviridae therapy.

3-Deazauridine 준비 용품 및 원자재

원자재

준비 용품

3-Deazauridine 공급 업체

글로벌( 71)공급 업체

공급자	전화	이메일	국가	제품 수	이점
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD	0371-55159968 18137130222	haifeng.zhang@pannacean.com	China	387	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
ROSEWA HOLDING GROUP CO.,LIMITED	+86-023-62871537	sales@rosewachem.com	China	2830	58
Zhengzhou Granlen Sciences, ltd.	0371-85513397	info@granlen.com	China	1827	58

3-Deazauridine 관련 검색:

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