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Stallimycin

Stallimycin 구조식 이미지

카스 번호:: 636-47-5

상품명:: Stallimycin

동의어(영문):: Distamycin;Stallimycin;Distamycin-3;3-[4-[4-[4-(Formylamino)-1-methyl-1H-pyrrole-2-ylcarbonylamino]-1-methyl-1H-pyrrole-2-ylcarbonylamino]-1-methyl-1H-pyrrole-2-ylcarbonylamino]propanamidine;N-[5-[[(3-Amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-4-[[[4-(formylamino)-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-1H-pyrrole-2-carboxamide;1H-Pyrrole-2-carboxamide, N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-4-[[[4-(formylamino)-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-

CBNumber:: CB51179775

분자식:: C22H27N9O4

포뮬러 무게:: 481.51

MOL 파일:: 636-47-5.mol

속성

안전

용도

공급 업체 8

Stallimycin 속성

녹는점: 154-156°

끓는 점: 579.2°C (rough estimate)

밀도: 1.3298 (rough estimate)

굴절률: 1.6910 (estimate)

안전

Stallimycin C화학적 특성, 용도, 생산

Originator

Herperal,Farmitalia,Italy,1978

Manufacturing Process

A spore suspension obtained upon washing a culture of Streptomyces distallicus is added to 3,000 ml of a sterile medium consisting of the following:Dextrose 2% Corn steep liquor extract 2% CaCO3 1% (NH4)2SO4 0.3% NaCl 0.3%Fermentation is continued at 28°C for 40 hours at a stirring rate of 150 to 250 rpm and a rate of air flow of 1 to 2 l/min/l of culture medium.
300 ml of a suspension of the vegetative mycelium of this culture are used for inoculating 6,000 ml of a similar sterile culture medium. At this production stage, the culture is kept fermenting for 85 to 100 hours (pH 7.6 at 28°C) at a stirring rate of 350 to 450 rpm and a rate of air flow of 1 to 1.5 l/min/l of culture medium.
To 17 l of a culture obtained by submerged fermentation as mentioned above, siliceous earth is added and the batch is filtered. The mixture of mycelium and the siliceous earth are agitated for 1 hour with 2.5 l of butanol. This treatment is repeated twice. The butanolic extracts are combined, washed with water, evaporated to dryness (about 10 g) and boiled with acetone (80 ml). The 5 g of distamycin is extracted six times with ethanol. The ethanolic extracts are combined, concentrated and filtered through a column containing 70 g of alumina. Elution is carried out with the same solvent. The effluent (central fractions) is collected and evaporated to dryness to yield 0.43 g of pure distamycin A: decomposition point, 183°C to 185°C. The product can be further purified by crystallization from aqueous n-butanol.

Therapeutic Function

Antibiotic

Stallimycin 준비 용품 및 원자재

원자재

옥수수 침지액 말토덱스트린

준비 용품

Stallimycin 공급 업체

글로벌( 8)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Zhejiang Huida Biotech Co., LTD	0571-89903882 13626641628	jiangnan@huidabiotech.com	China	3661	58
Hubei Zhongshan Medical Technology Co., Ltd	027-61907345 13397111514	w13397111514@163.com	China	993	58
Zhejiang Huida Biotech Co., LTD	0571-0571-89903882 15990081639	sunshixuan@huidabiotech.com	China	3705	58
Hangzhou Hesheng Taiyi Biotechnology Co. , Ltd.	15868607770	hstysales@126.com	China	1160	58
Shanghai Yanchun Biopharmaceutical Technology Co., Ltd	4001-009266 17349750668	product@sci-e.com	China	2812	58

Stallimycin 관련 검색:

1H-Pyrrole-2-carboxamide, 4-(((4-((((aminoiminomethyl)amino)acetyl)ami no)-1-methyl-1H-pyrrol-2-yl)carbonyl)amino)-N-(5-(((3-amino-3-iminopro pyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-1-methyl-, dihydrochlorid e 1H-Pyrrole-2-carboxamide, 4-(((4-((((aminoiminomethyl)amino)acetyl)ami no)-1-methyl-1H-pyrrol-2-yl)carbonyl)amino)-N-(5-(((2-(aminoiminomethy l)-1-methylethyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-1-methyl-, d ihydrochloride Stallimycin DISTAMYCIN A HYDROCHLORIDE Tallimustine