1,3-dipropyl-8-(3-noradamantyl)xanthine

1,3-dipropyl-8-(3-noradamantyl)xanthine 구조식 이미지
카스 번호:
136199-02-5
상품명:
1,3-dipropyl-8-(3-noradamantyl)xanthine
동의어(영문):
MK-7418;KW-3902;HMR-4902;Rolofylline;KW-3902 >=98% (HPLC);1,3-dipropyl-8-(3-noradamantyl)xanthine;8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione;8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione;1H-Purine-2,6-dione, 8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-
CBNumber:
CB51337919
분자식:
C20H28N4O2
포뮬러 무게:
356.46
MOL 파일:
136199-02-5.mol
MSDS 파일:
SDS

1,3-dipropyl-8-(3-noradamantyl)xanthine 속성

끓는 점
578.0±42.0 °C(Predicted)
밀도
1.262±0.06 g/cm3(Predicted)
저장 조건
2-8°C
용해도
DMSO: 가용성20mg/mL
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
9.23±0.70(Predicted)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
WGK 독일 3
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H413 장기적 영향에 의해 수생생물에 유해의 우려가 있음 수생 환경유해성 물질 - 만성 구분 4
예방조치문구:

1,3-dipropyl-8-(3-noradamantyl)xanthine C화학적 특성, 용도, 생산

개요

KW 3902 is an antagonist of the adenosine A1 receptor (Ki = 0.19 nM). It displays 890-fold selectivity for A1 receptors over A2A receptors and has no activity at A3 receptors. KW 3902 less potently inhibits human organic anion transporter 1 (OAT1; Ki = 7.82 μM). KW 3902 exhibits renal protective effects during hypoxemia in rabbits.

용도

KW 3902 is an adenosine A1-receptor antagonist, which has recently been shown to alleviate axonopathy caused by human Tau ΔK280. KW 3902 can be considered for the development of a treatment towards hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases.

1,3-dipropyl-8-(3-noradamantyl)xanthine 준비 용품 및 원자재

원자재

준비 용품


1,3-dipropyl-8-(3-noradamantyl)xanthine 공급 업체

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TargetMol Chemicals Inc.
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Career Henan Chemica Co
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Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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Energy Chemical 021-58432009 400-005-6266
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