Guanadrel HeMisulfate

Guanadrel HeMisulfate 구조식 이미지
카스 번호:
22195-34-2
상품명:
Guanadrel HeMisulfate
동의어(영문):
Anarel;Hylorel;U-28288D;CL-1388R;Hyloride;CHEBI:5556;Guanadrel HeMisulfate;GUANADREL SULFATE (200 MG);(1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate;N-(1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate
CBNumber:
CB5501416
분자식:
C10H19N3O2.H2O4S
포뮬러 무게:
311.357
MOL 파일:
22195-34-2.mol

Guanadrel HeMisulfate 속성

녹는점
213.5-215°

안전

유해 물질 데이터 22195-34-2(Hazardous Substances Data)

Guanadrel HeMisulfate C화학적 특성, 용도, 생산

용도

Guanadrel is an orally active postganglionic sympathetic inhibitor. Guanadrel HeMisulfate is used as an antihypertensive.

정의

ChEBI: A sulfate salt resulting from the reaction of 2 eq. guanadrel with 1 eq. sulfuric acid. A postganglionic adrenergic blocking agent formerly used for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthosta ic hypotension (dizzy spells on standing up or stretching).

일반 설명

Guanadrel sulfate, (1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanadine sulfate (Hylorel), issimilar to guanethidine monosulfate in the manner in whichit reduces elevated blood pressure. It acts as a postganglionicadrenergic blocking agent by displacing norepinephrinein adrenergic neuron storage granules, therebypreventing release of the endogenous neurotransmitter onnerve stimulation. Guanadrel sulfate has a much shorterhalf-life (10 hours) than guanethidine monosulfate, whose half-life is measured in days. In the stepped-care approachto hypertension, guanadrel sulfate is usually a step 2 agent.

Guanadrel HeMisulfate 준비 용품 및 원자재

원자재

준비 용품


Guanadrel HeMisulfate 공급 업체

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