AG 1295

AG 1295 구조식 이미지
카스 번호:
71897-07-9
상품명:
AG 1295
동의어(영문):
AG 1295;NSC 380341;AG 1295 USP/EP/BP;TYRPHOSTIN AG 1295;TYROPHOSTIN AG1295;AG-1295 (NSC 380341;TYRPHOSTIN AG 1295, 99+%;AG 1295 PLATELET-DERIVED GROW;6,7-DIMETHYL-2-PHENYLQUINOXALINE;Quinoxaline, 6,7-dimethyl-2-phenyl-
CBNumber:
CB5683675
분자식:
C16H14N2
포뮬러 무게:
234.3
MOL 파일:
71897-07-9.mol
MSDS 파일:
SDS

AG 1295 속성

녹는점
121 °C
끓는 점
398.3±37.0 °C(Predicted)
밀도
1.127±0.06 g/cm3(Predicted)
저장 조건
−20°C
용해도
클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)
물리적 상태
흰색 고체
산도 계수 (pKa)
1.29±0.30(Predicted)
색상
노란색

안전

안전지침서 22-24/25
WGK 독일 3

AG 1295 C화학적 특성, 용도, 생산

개요

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the treatment of atherosclerosis, restenosis, pulmonary fibrosis, and gliomas. AG-1295 is a quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC50s range from 0.3-1 μM). It inhibits PDGF-stimulated DNA synthesis with an IC50 value of 2.5 μM without affecting activity of the EGF receptor.

용도

AG-1295 is a protein tyrosine kinase inhibitor. Antiproliferative agent used in the treatment of atherosclerosis, pulmonary fibrosis, and gliomas.

AG 1295 준비 용품 및 원자재

원자재

준비 용품


AG 1295 공급 업체

글로벌( 71)공급 업체
공급자 전화 이메일 국가 제품 수 이점
career henan chemical co
+86-0371-86658258
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Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd
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sales@chemdad.com China 39916 58
TargetMol Chemicals Inc.
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marketing@targetmol.com United States 19892 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 29067 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277
marketing_china@spectrumchemical.com China 9664 60
Struchem Co., Ltd. 0512-0512-63009836 15365350169
helen@struchem.com China 3989 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9709 58

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